Version 5.4
Mus musculus Gene: Klra2
Summary
InnateDB Gene IDBG-193255.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Klra2
Gene Name killer cell lectin-like receptor, subfamily A, member 2
Synonyms Klra30; Ly49b
Species Mus musculus
Ensembl Gene ENSMUSG00000030187
Encoded Proteins
IDBP-163136
killer cell lectin-like receptor, subfamily A, member 2
IDBP-193257
killer cell lectin-like receptor, subfamily A, member 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The gene is a member of the large lectin-like type 2 transmembrane receptor family of the natural killer gene complex. The gene is located distantly telomeric to its family's gene cluster on chromosome 6. The gene differs from the other genes in its cluster as its promoter region contains long and short interspersed repetitive elements suggesting a possible rearrangement or gene conversion. It is unknown whether this gene's encoded protein is involved with natural killer cell differentiation as are its other family members. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2010]
The gene is a member of the large lectin-like type 2 transmembrane receptor family of the natural killer gene complex. The gene is located distantly telomeric to its family\'s gene cluster on chromosome 6. The gene differs from the other genes in its cluster as its promoter region contains long and short interspersed repetitive elements suggesting a possible rearrangement or gene conversion. It is unknown whether this gene\'s encoded protein is involved with natural killer cell differentiation as are its other family members. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 6:131219223-131247362
Strand Reverse strand
Band F3
Transcripts
ENSMUST00000088867 ENSMUSP00000086252
ENSMUST00000032306 ENSMUSP00000032306
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0030246 carbohydrate binding
Biological Process
Cellular Component
GO:0005886 plasma membrane
Orthologs
No orthologs found for this gene
Cross-References
SwissProt
TrEMBL E9Q433
UniProt Splice Variant
Entrez Gene 16633
UniGene Mm.4783
RefSeq NM_001170851 XM_006505645 NM_008462 XM_006505641 XM_006505642
OMIM
CCDS CCDS51929 CCDS20603
HPRD
IMGT
MGI ID MGI:101906
MGI Symbol Klra2
EMBL AC148326 AC163356
GenPept
RNA Seq Atlas 16633

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca