Version 5.4
| Mus musculus Gene: Pspn | |||||||
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| Summary | |||||||
| InnateDB Gene | IDBG-193294.6 | ||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||
| Gene Symbol | Pspn | ||||||
| Gene Name | persephin | ||||||
| Synonyms | PSP | ||||||
| Species | Mus musculus | ||||||
| Ensembl Gene | ENSMUSG00000002664 | ||||||
| Encoded Proteins |
persephin
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| Protein Structure | |||||||
| Useful resources | Stemformatics EHFPI ImmGen | ||||||
| Entrez Gene | |||||||
| Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000125650:
The protein encoded by this gene is a neurotrophic factor, belonging to the GDNF family. Neurotrophic factors are important for the proper development and maintenance of the nervous system. These factors promote neuronal survival and can prevent the neuronal degeneration associated with injury, toxin exposure, or neurodegenerative disease. The encoded protein has amino acid similarity to its other family members, glial cell line-derived neurotrophic factor and neurturin. This gene product promotes the survival of ventral midbrain dopaminergic neurons in culture and prevents their degeneration after 6-hydroxydopamine treatment in vivo. [provided by RefSeq, Jul 2008] |
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| Gene Information | |||||||
| Type | Protein coding | ||||||
| Genomic Location | Chromosome 17:56999457-57000018 | ||||||
| Strand | Reverse strand | ||||||
| Band | D | ||||||
| Transcripts |
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| Interactions | |||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||
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Species
Homo sapiens
Bos taurus
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Gene ID
Gene Order
Not yet available
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| Pathway Predictions based on Human Orthology Data | |||||||
| NETPATH | |||||||
| REACTOME |
NCAM1 interactions pathway
NCAM signaling for neurite out-growth pathway
Developmental Biology pathway
Axon guidance pathway
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| KEGG | |||||||
| INOH | |||||||
| PID NCI | |||||||
| Cross-References | |||||||
| SwissProt | |||||||
| TrEMBL | A1L3Q1 | ||||||
| UniProt Splice Variant | |||||||
| Entrez Gene | 19197 | ||||||
| UniGene | Mm.86487 | ||||||
| RefSeq | NM_008954 | ||||||
| OMIM | |||||||
| CCDS | CCDS28922 | ||||||
| HPRD | |||||||
| IMGT | |||||||
| MGI ID | MGI:1201684 | ||||||
| MGI Symbol | Pspn | ||||||
| EMBL | AC073683 BC130229 CH466537 | ||||||
| GenPept | AAI30230 EDL38218 | ||||||
| RNA Seq Atlas | 19197 | ||||||