Mus musculus Gene: Mrpl46
Summary
InnateDB Gene IDBG-193440.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Mrpl46
Gene Name mitochondrial ribosomal protein L46
Synonyms 3110052F15Rik; C15orf4; C80107; LIECG2; P2ECSL
Species Mus musculus
Ensembl Gene ENSMUSG00000030612
Encoded Proteins
mitochondrial ribosomal protein L46
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000259494:
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 7:78775236-78783531
Strand Reverse strand
Band D2
Transcripts
ENSMUST00000032841 ENSMUSP00000032841
ENSMUST00000133949
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 12 interaction(s) predicted by orthology.
Predicted by orthology
Total 12 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0016787 hydrolase activity
Biological Process
GO:0008150 biological_process
GO:0008152 metabolic process
Cellular Component
GO:0005739 mitochondrion
GO:0005840 ribosome
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Not yet available
Pathways
NETPATH
REACTOME
Mitochondrial translation pathway
Organelle biogenesis and maintenance pathway
Mitochondrial translation elongation pathway
Mitochondrial translation initiation pathway
Mitochondrial translation termination pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
Organelle biogenesis and maintenance pathway
Mitochondrial translation pathway
Mitochondrial translation initiation pathway
Mitochondrial translation termination pathway
Mitochondrial translation elongation pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt Q9EQI8
TrEMBL
UniProt Splice Variant
Entrez Gene 67308
UniGene
RefSeq NM_023331
OMIM
CCDS CCDS21373
HPRD
IMGT
MGI ID MGI:1914558
MGI Symbol Mrpl46
EMBL AF217090 BC061094
GenPept AAG44099 AAH61094
RNA Seq Atlas 67308