Version 5.4
Mus musculus Gene: Adipor1
Summary
InnateDB Gene IDBG-193768.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Adipor1
Gene Name adiponectin receptor 1
Synonyms 2810031L11Rik; ACDCR1; CGI-45; Paqr1
Species Mus musculus
Ensembl Gene ENSMUSG00000026457
Encoded Proteins
IDBP-193770
adiponectin receptor 1
IDBP-256427
adiponectin receptor 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000159346:
This gene encodes a protein which acts as a receptor for adiponectin, a hormone secreted by adipocytes which regulates fatty acid catabolism and glucose levels. Binding of adiponectin to the encoded protein results in activation of an AMP-activated kinase signaling pathway which affects levels of fatty acid oxidation and insulin sensitivity. A pseudogene of this gene is located on chromosome 14. [provided by RefSeq, Jan 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 1:134415378-134433351
Strand Forward strand
Band E4
Transcripts
ENSMUST00000027727 ENSMUSP00000027727
ENSMUST00000112237 ENSMUSP00000107856
ENSMUST00000156433
ENSMUST00000148822
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 8 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 8 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004872 receptor activity
GO:0005515 protein binding
GO:0019901 protein kinase binding
GO:0042562 hormone binding
GO:0042802 identical protein binding
GO:0046982 protein heterodimerization activity
GO:0055100 adiponectin binding
Biological Process
GO:0009755 hormone-mediated signaling pathway
GO:0019395 fatty acid oxidation
GO:0030308 negative regulation of cell growth
GO:0033210 leptin-mediated signaling pathway
GO:0033211 adiponectin-activated signaling pathway
GO:0046427 positive regulation of JAK-STAT cascade
GO:0046628 positive regulation of insulin receptor signaling pathway
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000159346
View Gene Order
ENSBTAG00000009727
Not yet available
Pathways
NETPATH
REACTOME
KEGG
mmu04920
Adipocytokine signaling pathway pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
hsa04920
Adipocytokine signaling pathway pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.259976 Mm.398249 Mm.472093
RefSeq NM_028320 XM_006529888
OMIM
CCDS CCDS15309
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca