InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Gene: Terf2ip

Summary

InnateDB Gene

IDBG-193961.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Terf2ip

Gene Name

telomeric repeat binding factor 2, interacting protein

Synonyms

Rap1

Species

Mus musculus

Ensembl Gene

ENSMUSG00000033430

Encoded Proteins

IDBP-193965

telomeric repeat binding factor 2, interacting protein

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000166848:
The gene encodes a protein that is part of a complex involved in telomere length regulation. Pseudogenes are present on chromosomes 5 and 22. [provided by RefSeq, Apr 2010]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 8:112011359-112020528

Strand

Forward strand

Band

Transcripts

ENSMUST00000052138

ENSMUSP00000052170

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 129 interaction(s) predicted by orthology.

Experimentally validated
Total	2 [view]
Protein-Protein	2 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	129 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003677	DNA binding
GO:0005515	protein binding

Biological Process

GO:0000723	telomere maintenance
GO:0006351	transcription, DNA-templated
GO:0006355	regulation of transcription, DNA-templated
GO:0010569	regulation of double-strand break repair via homologous recombination
GO:0010833	telomere maintenance via telomere lengthening
GO:0031848	protection from non-homologous end joining at telomere
GO:0032205	negative regulation of telomere maintenance
GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0048239	negative regulation of DNA recombination at telomere
GO:0051092	positive regulation of NF-kappaB transcription factor activity
GO:0070198	protein localization to chromosome, telomeric region

Cellular Component

GO:0000781	chromosome, telomeric region
GO:0000783	nuclear telomere cap complex
GO:0000784	nuclear chromosome, telomeric region
GO:0005634	nucleus
GO:0005654	nucleoplasm
GO:0005737	cytoplasm
GO:0030870	Mre11 complex