Version 5.4
Mus musculus Gene: Alox12e
Summary
InnateDB Gene IDBG-194071.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Alox12e
Gene Name arachidonate lipoxygenase, epidermal
Synonyms 8-LOX; Alox12-ps1; Alox12-ps2; Aloxe; AW259591; e-LOX1
Species Mus musculus
Ensembl Gene ENSMUSG00000018907
Encoded Proteins
IDBP-194073
arachidonate lipoxygenase, epidermal
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 11:70315610-70322628
Strand Reverse strand
Band B3
Transcripts
ENSMUST00000019051 ENSMUSP00000019051
ENSMUST00000123752
ENSMUST00000139899
ENSMUST00000149060
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0004052 arachidonate 12-lipoxygenase activity
GO:0005506 iron ion binding
GO:0005515 protein binding
GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
GO:0046872 metal ion binding
Biological Process
GO:0019369 arachidonic acid metabolic process
GO:0019372 lipoxygenase pathway
GO:0055114 oxidation-reduction process
Cellular Component
GO:0005737 cytoplasm
Orthologs
No orthologs found for this gene
Pathways
NETPATH
REACTOME
KEGG
mmu00590
Arachidonic acid metabolism pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.274093
RefSeq NM_145684 XM_006532034 XM_006532035 XM_006537112 XM_006537113
OMIM
CCDS CCDS24943
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca