Version 5.4
Mus musculus Gene: Cd59a
Summary
InnateDB Gene IDBG-194302.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Cd59a
Gene Name CD59a antigen
Synonyms AA987121; Cd59; protectin
Species Mus musculus
Ensembl Gene ENSMUSG00000032679
Encoded Proteins
IDBP-194304
CD59a antigen
IDBP-625754
CD59a antigen
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 2:104095801-104115354
Strand Forward strand
Band E2
Transcripts
ENSMUST00000040423 ENSMUSP00000048041
ENSMUST00000153312
ENSMUST00000168176 ENSMUSP00000132774
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0001848 complement binding
Biological Process
GO:0001775 cell activation
GO:0001971 negative regulation of activation of membrane attack complex
GO:0016525 negative regulation of angiogenesis
GO:0030948 negative regulation of vascular endothelial growth factor receptor signaling pathway
GO:0045916 negative regulation of complement activation
GO:0090272 negative regulation of fibroblast growth factor production
Cellular Component
GO:0005576 extracellular region
GO:0009897 external side of plasma membrane
GO:0031225 anchored component of membrane
Orthologs
No orthologs found for this gene
Pathways
NETPATH
REACTOME
REACT_239142
Innate Immune System pathway
REACT_208792
Complement cascade pathway
REACT_198562
Regulation of Complement cascade pathway
REACT_230745
Immune System pathway
KEGG
mmu04640
Hematopoietic cell lineage pathway
mmu04610
Complement and coagulation cascades pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.247265
RefSeq NM_001111060 NM_007652 XM_006498650 XM_006498651
OMIM
CCDS CCDS16487
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca