Version 5.4
Mus musculus Gene: Ddx47
Summary
InnateDB Gene IDBG-194403.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Ddx47
Gene Name DEAD (Asp-Glu-Ala-Asp) box polypeptide 47
Synonyms 4930588A18Rik; C77285
Species Mus musculus
Ensembl Gene ENSMUSG00000030204
Encoded Proteins
IDBP-194405
DEAD (Asp-Glu-Ala-Asp) box polypeptide 47
IDBP-534199
DEAD (Asp-Glu-Ala-Asp) box polypeptide 47
IDBP-540371
DEAD (Asp-Glu-Ala-Asp) box polypeptide 47
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000213782:
This gene encodes a member of the DEAD box protein family. DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. The protein encoded by this gene can shuttle between the nucleus and the cytoplasm, and has an RNA-independent ATPase activity. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 6:135011612-135023776
Strand Forward strand
Band G1
Transcripts
ENSMUST00000032326 ENSMUSP00000032326
ENSMUST00000130851 ENSMUSP00000115183
ENSMUST00000131719
ENSMUST00000155277
ENSMUST00000155698
ENSMUST00000154558 ENSMUSP00000119231
ENSMUST00000123022
ENSMUST00000134549
ENSMUST00000155022
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
They are also associated with 18 interaction(s) predicted by orthology.
Experimentally validated
Total 5 [view]
Protein-Protein 5 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 18 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003676 nucleic acid binding
GO:0003723 RNA binding
GO:0004386 helicase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0008026 ATP-dependent helicase activity
GO:0044822 poly(A) RNA binding
Biological Process
GO:0006200 ATP catabolic process
GO:0006364 rRNA processing
GO:0006397 mRNA processing
GO:0008152 metabolic process
GO:0008380 RNA splicing
GO:0008625 extrinsic apoptotic signaling pathway via death domain receptors
Cellular Component
GO:0005730 nucleolus
GO:0016020 membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000213782
View Gene Order
ENSBTAG00000019608
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.166524
RefSeq NM_026360
OMIM
CCDS CCDS20643
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca