Homo sapiens Gene: RPL32
Summary
InnateDB Gene IDBG-19461.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol RPL32
Gene Name ribosomal protein L32
Synonyms L32
Species Homo sapiens
Ensembl Gene ENSG00000144713
Encoded Proteins
ribosomal protein L32
ribosomal protein L32
ribosomal protein L32
ribosomal protein L32
ribosomal protein L32
ribosomal protein L32
ribosomal protein L32
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L32E family of ribosomal proteins. It is located in the cytoplasm. Although some studies have mapped this gene to 3q13.3-q21, it is believed to map to 3p25-p24. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. Alternatively spliced transcript variants encoding the same protein have been observed for this gene. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 3:12834485-12841588
Strand Reverse strand
Band p25.2
Transcripts
ENST00000273223 ENSP00000339064
ENST00000396957 ENSP00000380158
ENST00000396953 ENSP00000380156
ENST00000429711 ENSP00000416429
ENST00000435983 ENSP00000388674
ENST00000457131 ENSP00000412393
ENST00000452606
ENST00000434963 ENSP00000413742
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 57 experimentally validated interaction(s) in this database.
Experimentally validated
Total 57 [view]
Protein-Protein 56 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003735 structural constituent of ribosome
GO:0044822 poly(A) RNA binding
Biological Process
GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
GO:0006412 translation
GO:0006413 translational initiation
GO:0006414 translational elongation
GO:0006415 translational termination
GO:0006614 SRP-dependent cotranslational protein targeting to membrane
GO:0010467 gene expression
GO:0016032 viral process
GO:0016070 RNA metabolic process
GO:0016071 mRNA metabolic process
GO:0019058 viral life cycle
GO:0019083 viral transcription
GO:0044267 cellular protein metabolic process
Cellular Component
GO:0005622 intracellular
GO:0005829 cytosol
GO:0005840 ribosome
GO:0016020 membrane
GO:0022625 cytosolic large ribosomal subunit
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Not yet available
Pathways
NETPATH
REACTOME
L13a-mediated translational silencing of Ceruloplasmin expression pathway
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) pathway
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) pathway
GTP hydrolysis and joining of the 60S ribosomal subunit pathway
Formation of a pool of free 40S subunits pathway
Eukaryotic Translation Termination pathway
Peptide chain elongation pathway
Eukaryotic Translation Elongation pathway
SRP-dependent cotranslational protein targeting to membrane pathway
Viral mRNA Translation pathway
Eukaryotic Translation Initiation pathway
Influenza Infection pathway
Nonsense-Mediated Decay (NMD) pathway
Influenza Viral RNA Transcription and Replication pathway
Translation pathway
Metabolism of proteins pathway
Cap-dependent Translation Initiation pathway
Influenza Life Cycle pathway
Gene Expression pathway
Disease pathway
KEGG
Ribosome pathway
INOH
PID NCI
Cross-References
SwissProt P62910
TrEMBL A0A024R2G7 D3YTB1 D3YTI8
UniProt Splice Variant
Entrez Gene 6161
UniGene Hs.265174 Hs.711399
RefSeq NM_000994 NM_001007073 NM_001007074
HUGO HGNC:10336
OMIM
CCDS CCDS2614
HPRD 17995
IMGT
EMBL AB061831 AC034198 AF370435 AK311909 BC011514 BC070209 CH471055 X03342
GenPept AAH11514 AAH70209 AAQ15271 BAB79469 BAG34850 CAA27048 EAW64144 EAW64145
RNA Seq Atlas 6161