Version 5.4
Mus musculus Gene: Glyctk
Summary
InnateDB Gene IDBG-195616.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Glyctk
Gene Name glycerate kinase
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000020258
Encoded Proteins
IDBP-195618
glycerate kinase
IDBP-255800
glycerate kinase
IDBP-539862
glycerate kinase
IDBP-538431
glycerate kinase
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000168237:
This locus encodes a member of the glycerate kinase type-2 family. The encoded enzyme catalyzes the phosphorylation of (R)-glycerate and may be involved in serine degradation and fructose metabolism. Decreased activity of the encoded enzyme may be associated with the disease D-glyceric aciduria. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jan 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 9:106152857-106158138
Strand Reverse strand
Band F1
Transcripts
ENSMUST00000036382 ENSMUSP00000047761
ENSMUST00000112543 ENSMUSP00000108162
ENSMUST00000162562 ENSMUSP00000125392
ENSMUST00000159809 ENSMUSP00000125369
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0008887 glycerate kinase activity
Biological Process
GO:0006468 protein phosphorylation
Cellular Component
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005794 Golgi apparatus
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000168237
View Gene Order
ENSBTAG00000021695
Not yet available
Pathways
NETPATH
REACTOME
KEGG
mmu00260
Glycine, serine and threonine metabolism pathway
mmu00561
Glycerolipid metabolism pathway
mmu00630
Glyoxylate and dicarboxylate metabolism pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
hsa00260
Glycine, serine and threonine metabolism pathway
hsa00630
Glyoxylate and dicarboxylate metabolism pathway
hsa00561
Glycerolipid metabolism pathway
INOH
PID NCI
Cross-References
SwissProt Q8QZY2
TrEMBL E0CXF4 E0CZG7
UniProt Splice Variant
Entrez Gene 235582
UniGene Mm.335420
RefSeq NM_174846 NM_001039586
OMIM
CCDS CCDS23469
HPRD
IMGT
MGI ID MGI:2444085
MGI Symbol Glyctk
EMBL AC164430 AF455785 AK049425 AK050182 AK052709 BC025834 BC025935 BC030732 BC033063 BC036136
GenPept AAH25834 AAH25935 AAH30732 AAH33063 AAH36136 AAP97704 BAC33747 BAC34112 BAC35110
RNA Seq Atlas 235582

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca