Version 5.4
| Mus musculus Gene: Slc39a8 | |||||||||||||
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| Summary | |||||||||||||
| InnateDB Gene | IDBG-195635.6 | ||||||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||
| Gene Symbol | Slc39a8 | ||||||||||||
| Gene Name | solute carrier family 39 (metal ion transporter), member 8 | ||||||||||||
| Synonyms | 4933419D20Rik; AA986696; BIGM103; ZIP-8; Zip8 | ||||||||||||
| Species | Mus musculus | ||||||||||||
| Ensembl Gene | ENSMUSG00000053897 | ||||||||||||
| Encoded Proteins |
solute carrier family 39 (metal ion transporter), member 8
solute carrier family 39 (metal ion transporter), member 8
solute carrier family 39 (metal ion transporter), member 8
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| Protein Structure |
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| Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||
| Entrez Gene | |||||||||||||
| Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000138821:
This gene encodes a member of the SLC39 family of solute-carrier genes, which show structural characteristics of zinc transporters. The encoded protein is glycosylated and found in the plasma membrane and mitochondria, and functions in the cellular import of zinc at the onset of inflammation. It is also thought to be the primary transporter of the toxic cation cadmium, which is found in cigarette smoke. Multiple transcript variants encoding different isoforms have been found for this gene. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known. [provided by RefSeq, Oct 2008] |
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| Gene Information | |||||||||||||
| Type | Protein coding | ||||||||||||
| Genomic Location | Chromosome 3:135825279-135888572 | ||||||||||||
| Strand | Forward strand | ||||||||||||
| Band | G3 | ||||||||||||
| Transcripts |
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| Interactions | |||||||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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| Gene Ontology | |||||||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||||||
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Species
Homo sapiens
Bos taurus
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Gene ID
Gene Order
Not yet available
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| Pathways | |||||||||||||
| NETPATH | |||||||||||||
| REACTOME |
Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds pathway
SLC-mediated transmembrane transport pathway
Zinc influx into cells by the SLC39 gene family pathway
Zinc transporters pathway
Transmembrane transport of small molecules pathway
Metal ion SLC transporters pathway
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| KEGG | |||||||||||||
| INOH | |||||||||||||
| PID NCI | |||||||||||||
| Pathway Predictions based on Human Orthology Data | |||||||||||||
| NETPATH | |||||||||||||
| REACTOME |
Zinc influx into cells by the SLC39 gene family pathway
Metal ion SLC transporters pathway
Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds pathway
Transmembrane transport of small molecules pathway
Zinc transporters pathway
SLC-mediated transmembrane transport pathway
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| KEGG | |||||||||||||
| INOH | |||||||||||||
| PID NCI | |||||||||||||
| Cross-References | |||||||||||||
| SwissProt | Q91W10 | ||||||||||||
| TrEMBL | |||||||||||||
| UniProt Splice Variant | |||||||||||||
| Entrez Gene | 67547 | ||||||||||||
| UniGene | Mm.30239 Mm.490589 | ||||||||||||
| RefSeq | NM_001135149 NM_001135150 NM_026228 XM_006501934 XM_006501935 | ||||||||||||
| OMIM | |||||||||||||
| CCDS | CCDS17859 | ||||||||||||
| HPRD | |||||||||||||
| IMGT | |||||||||||||
| MGI ID | MGI:1914797 | ||||||||||||
| MGI Symbol | Slc39a8 | ||||||||||||
| EMBL | AK014895 AK016853 AK085740 AK089060 BC006731 | ||||||||||||
| GenPept | AAH06731 BAB29610 BAB30465 BAC39526 BAC40727 | ||||||||||||
| RNA Seq Atlas | 67547 | ||||||||||||