Version 5.4
Homo sapiens Gene: NMU
Summary
InnateDB Gene IDBG-19638.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol NMU
Gene Name neuromedin U
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000109255
Encoded Proteins
IDBP-19642
neuromedin U
IDBP-474435
neuromedin U
IDBP-482604
neuromedin U
IDBP-480569
neuromedin U
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 4:55595229-55636698
Strand Reverse strand
Band q12
Transcripts
ENST00000264218 ENSP00000264218
ENST00000511469 ENSP00000422399
ENST00000505262 ENSP00000424246
ENST00000507338 ENSP00000422870
ENST00000515325
ENST00000509371
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005102 receptor binding
GO:0042922 neuromedin U receptor binding
Biological Process
GO:0001696 gastric acid secretion
GO:0006940 regulation of smooth muscle contraction
GO:0007165 signal transduction
GO:0007186 G-protein coupled receptor signaling pathway
GO:0007218 neuropeptide signaling pathway
GO:0007586 digestion
GO:0009648 photoperiodism
GO:0019233 sensory perception of pain
GO:0042755 eating behavior
GO:0045987 positive regulation of smooth muscle contraction
GO:0046887 positive regulation of hormone secretion
GO:0050806 positive regulation of synaptic transmission
Cellular Component
GO:0005576 extracellular region
GO:0043195 terminal bouton
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000029236
View Gene Order
ENSBTAG00000044161
Not yet available
Pathways
NETPATH
REACTOME
REACT_18283
G alpha (q) signalling events pathway
REACT_120966
Gastrin-CREB signalling pathway via PKC and MAPK pathway
REACT_19231
G alpha (i) signalling events pathway
REACT_14819
Peptide ligand-binding receptors pathway
REACT_14828
Class A/1 (Rhodopsin-like receptors) pathway
REACT_14797
Signaling by GPCR pathway
REACT_111102
Signal Transduction pathway
REACT_19184
GPCR downstream signaling pathway
REACT_21340
GPCR ligand binding pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene
RefSeq NM_001292045 NM_001292046 NM_006681 XM_005265713
HUGO
OMIM
CCDS CCDS3501 CCDS75125
HPRD 05485
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca