Version 5.4
Mus musculus Gene: Gbp5
Summary
InnateDB Gene IDBG-197117.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Gbp5
Gene Name guanylate binding protein 5
Synonyms Gbp-1; Gbp1; Mag-1; Mpa-1; Mpa1
Species Mus musculus
Ensembl Gene ENSMUSG00000040264
Encoded Proteins
IDBP-197119
guanylate binding protein 5
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000154451:
Gene Information
Type Protein coding
Genomic Location Chromosome 3:142496934-142619179
Strand Forward strand
Band H1
Transcripts
ENSMUST00000090127 ENSMUSP00000087587
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 10 experimentally validated interaction(s) in this database.
Experimentally validated
Total 10 [view]
Protein-Protein 3 [view]
Protein-DNA 7 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003924 GTPase activity
GO:0005525 GTP binding
GO:0019002 GMP binding
GO:0042802 identical protein binding
Biological Process
GO:0006184 GTP catabolic process
GO:0035458 cellular response to interferon-beta
GO:0042832 defense response to protozoan
GO:0044406 adhesion of symbiont to host
GO:0050830 defense response to Gram-positive bacterium
GO:0071346 cellular response to interferon-gamma
Cellular Component
GO:0016020 membrane
GO:0020005 symbiont-containing vacuole membrane
GO:0031410 cytoplasmic vesicle
Orthologs
Species
Homo sapiens
Gene ID
Gene Order
ENSG00000154451
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_25078
Interferon gamma signaling pathway
REACT_75790
Cytokine Signaling in Immune system pathway
REACT_25229
Interferon Signaling pathway
REACT_6900
Immune System pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt Q8CFB4
TrEMBL
UniProt Splice Variant
Entrez Gene 229898
UniGene Mm.459245
RefSeq NM_153564 NM_010259 XM_006500999 XM_006544774
OMIM
CCDS CCDS17877 CCDS38658
HPRD
IMGT
MGI ID MGI:2429943
MGI Symbol Gbp5
EMBL AC102108 AF422243 AY128412 BC058555
GenPept AAH58555 AAN31451 AAN46362
RNA Seq Atlas 102643136 14468 229898

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca