Version 5.4
Homo sapiens Gene: THAP10
Summary
InnateDB Gene IDBG-19774.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol THAP10
Gene Name THAP domain containing 10
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000129028
Encoded Proteins
IDBP-19776
THAP domain containing 10
IDBP-586488
THAP domain containing 10
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a member of a family of proteins sharing an N-terminal Thanatos-associated domain. The Thanatos-associated domain contains a zinc finger signature similar to DNA-binding domains. This gene is part of a bidirectional gene pair on the long arm of chromosome 15 that is regulated by estrogen and may play a role in breast cancer. [provided by RefSeq, Nov 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 15:70881342-70892785
Strand Reverse strand
Band q23
Transcripts
ENST00000249861 ENSP00000249861
ENST00000560604 ENSP00000453920
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
Experimentally validated
Total 5 [view]
Protein-Protein 3 [view]
Protein-DNA 2 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0046872 metal ion binding
Biological Process
Cellular Component
Orthologs
No orthologs found for this gene
Cross-References
SwissProt Q9P2Z0
TrEMBL
UniProt Splice Variant
Entrez Gene 56906
UniGene Hs.591123 Hs.732115
RefSeq NM_020147
HUGO HGNC:23193
OMIM 612538
CCDS CCDS10237
HPRD 15497
IMGT
EMBL AK313472 AL360202 BC027857 BC072414 CH471082
GenPept AAH27857 AAH72414 BAG36257 CAB96109 EAW77863
RNA Seq Atlas 56906

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca