Version 5.4
Mus musculus Gene: Hmcn1
Summary
InnateDB Gene IDBG-197771.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Hmcn1
Gene Name hemicentin 1
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000066842
Encoded Proteins
IDBP-197773
hemicentin 1
IDBP-542264
hemicentin 1
IDBP-716931
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000143341:
This gene encodes a large extracellular member of the immunoglobulin superfamily. A similar protein in C. elegans forms long, fine tracks at specific extracellular sites that are involved in many processes such as stabilization of the germline syncytium, anchorage of mechanosensory neurons to the epidermis, and organization of hemidesmosomes in the epidermis. Mutations in this gene may be associated with age-related macular degeneration. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 1:150562524-150993435
Strand Reverse strand
Band G1
Transcripts
ENSMUST00000074783 ENSMUSP00000074340
ENSMUST00000137197 ENSMUSP00000121500
ENSMUST00000151899
ENSMUST00000137909
ENSMUST00000155715
ENSMUST00000177036 ENSMUSP00000134985
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0005509 calcium ion binding
GO:0005515 protein binding
Biological Process
GO:0008150 biological_process
Cellular Component
GO:0005576 extracellular region
GO:0005604 basement membrane
GO:0005938 cell cortex
GO:0030054 cell junction
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000143341
View Gene Order
ENSBTAG00000015235
Not yet available
Cross-References
SwissProt
TrEMBL D3Z2Q7
UniProt Splice Variant
Entrez Gene 545370
UniGene Mm.379425
RefSeq NM_001024720
OMIM
CCDS CCDS15357
HPRD
IMGT
MGI ID MGI:2685047
MGI Symbol Hmcn1
EMBL AC111145 AC113326 AC115051 AC124120
GenPept
RNA Seq Atlas 545370

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca