Mus musculus Gene: Rassf8
Summary
InnateDB Gene IDBG-197849.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Rassf8
Gene Name Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
Synonyms 5133400D11Rik; AA815821; AW123240; Hoj1; mHoj-1
Species Mus musculus
Ensembl Gene ENSMUSG00000030259
Encoded Proteins
Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000123094:
This gene encodes a member of the Ras-assocation domain family (RASSF) of tumor suppressor proteins. This gene is essential for maintaining adherens junction function in epithelial cells and has a role in epithelial cell migration. It is a lung tumor suppressor gene candidate. A chromosomal translocation t(12;22)(p11.2;q13.3) leading to the fusion of this gene and the FBLN1 gene is found in a complex type of synpolydactyly. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 6:145746748-145821079
Strand Forward strand
Band G3
Transcripts
ENSMUST00000032388 ENSMUSP00000032388
ENSMUST00000111704 ENSMUSP00000107333
ENSMUST00000140966 ENSMUSP00000122684
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 12 interaction(s) predicted by orthology.
Predicted by orthology
Total 12 [view]
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0007165 signal transduction
Cellular Component
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Not yet available
Cross-References
SwissProt Q8CJ96
TrEMBL E9QA00
UniProt Splice Variant
Entrez Gene 71323
UniGene Mm.146001 Mm.158669 Mm.413408 Mm.444985 Mm.487351 Mm.489112
RefSeq NM_027760
OMIM
CCDS CCDS20696
HPRD
IMGT
MGI ID MGI:1918573
MGI Symbol Rassf8
EMBL AC138117 AF424737 AK017214 AK031980 BC115779 BC117546
GenPept AAI15780 AAI17547 AAN28310 BAB30637 BAC27637
RNA Seq Atlas 71323