Mus musculus Gene: Hnrnpr | |||||||||||||||||||||||
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Summary | |||||||||||||||||||||||
InnateDB Gene | IDBG-197957.6 | ||||||||||||||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||||||||||
Gene Symbol | Hnrnpr | ||||||||||||||||||||||
Gene Name | heterogeneous nuclear ribonucleoprotein R | ||||||||||||||||||||||
Synonyms | 2610003J05Rik; 2610528B01Rik; Hnrpr | ||||||||||||||||||||||
Species | Mus musculus | ||||||||||||||||||||||
Ensembl Gene | ENSMUSG00000066037 | ||||||||||||||||||||||
Encoded Proteins |
heterogeneous nuclear ribonucleoprotein R
heterogeneous nuclear ribonucleoprotein R
heterogeneous nuclear ribonucleoprotein R
heterogeneous nuclear ribonucleoprotein R
heterogeneous nuclear ribonucleoprotein R
heterogeneous nuclear ribonucleoprotein R
heterogeneous nuclear ribonucleoprotein R
heterogeneous nuclear ribonucleoprotein R
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Protein Structure | |||||||||||||||||||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||||||||||
Entrez Gene | |||||||||||||||||||||||
Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000125944:
This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has three repeats of quasi-RRM domains that bind to RNAs and also contains a nuclear localization motif. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2008] This gene encodes an RNA-binding protein that is a member of the spliceosome C complex, which functions in pre-mRNA processing and transport. The encoded protein also promotes transcription at the c-fos gene. Alternative splicing results in multiple transcript variants. There are pseudogenes for this gene on chromosomes 4, 11, and 10. [provided by RefSeq, Jul 2014] |
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Gene Information | |||||||||||||||||||||||
Type | Protein coding | ||||||||||||||||||||||
Genomic Location | Chromosome 4:136310942-136345981 | ||||||||||||||||||||||
Strand | Forward strand | ||||||||||||||||||||||
Band | D3 | ||||||||||||||||||||||
Transcripts | |||||||||||||||||||||||
Interactions | |||||||||||||||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 121 interaction(s) predicted by orthology.
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Gene Ontology | |||||||||||||||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||||||||||||||||||
Species
Homo sapiens
Bos taurus
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Gene ID
Gene Order
Not yet available
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Pathway Predictions based on Human Orthology Data | |||||||||||||||||||||||
NETPATH |
EGFR1 pathway
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REACTOME |
mRNA Splicing - Major Pathway pathway
Processing of Capped Intron-Containing Pre-mRNA pathway
mRNA Splicing pathway
Gene Expression pathway
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KEGG | |||||||||||||||||||||||
INOH | |||||||||||||||||||||||
PID NCI | |||||||||||||||||||||||
Cross-References | |||||||||||||||||||||||
SwissProt | |||||||||||||||||||||||
TrEMBL | A2AW40 | ||||||||||||||||||||||
UniProt Splice Variant | |||||||||||||||||||||||
Entrez Gene | 74326 | ||||||||||||||||||||||
UniGene | Mm.31051 Mm.313380 Mm.402394 Mm.406838 | ||||||||||||||||||||||
RefSeq | NM_001277121 NM_001277122 NM_001277123 NM_028871 XM_006539221 XM_006539222 XM_006539226 XM_006539227 XM_006539228 | ||||||||||||||||||||||
OMIM | |||||||||||||||||||||||
CCDS | CCDS18805 CCDS71495 | ||||||||||||||||||||||
HPRD | |||||||||||||||||||||||
IMGT | |||||||||||||||||||||||
MGI ID | MGI:1891692 | ||||||||||||||||||||||
MGI Symbol | Hnrnpr | ||||||||||||||||||||||
EMBL | AL670673 AL935264 BX537311 | ||||||||||||||||||||||
GenPept | |||||||||||||||||||||||
RNA Seq Atlas | 74326 | ||||||||||||||||||||||