Version 5.4
Mus musculus Gene: Cdh15
Summary
InnateDB Gene IDBG-198060.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Cdh15
Gene Name cadherin 15
Synonyms AI323380; Cdh14; Mcad
Species Mus musculus
Ensembl Gene ENSMUSG00000031962
Encoded Proteins
IDBP-198062
cadherin 15
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000129910:
This gene is a member of the cadherin superfamily of genes, encoding calcium-dependent intercellular adhesion glycoproteins. Cadherins consist of an extracellular domain containing 5 cadherin domains, a transmembrane region, and a conserved cytoplasmic domain. Transcripts from this particular cadherin are expressed in myoblasts and upregulated in myotubule-forming cells. The protein is thought to be essential for the control of morphogenetic processes, specifically myogenesis, and may provide a trigger for terminal muscle cell differentiation. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 8:122848374-122867397
Strand Forward strand
Band E1
Transcripts
ENSMUST00000034443 ENSMUSP00000034443
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005509 calcium ion binding
GO:0005515 protein binding
Biological Process
GO:0007156 homophilic cell adhesion
Cellular Component
GO:0005901 caveola
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0031594 neuromuscular junction
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000129910
View Gene Order
ENSBTAG00000011530
Not yet available
Pathways
NETPATH
REACTOME
REACT_248094
Cell-cell junction organization pathway
REACT_253473
Myogenesis pathway
REACT_258600
CDO in myogenesis pathway
REACT_230395
Adherens junctions interactions pathway
REACT_188576
Developmental Biology pathway
REACT_241978
Cell junction organization pathway
REACT_223082
Cell-Cell communication pathway
KEGG
mmu04514
Cell adhesion molecules (CAMs) pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_19195
Adherens junctions interactions pathway
REACT_21402
CDO in myogenesis pathway
REACT_111045
Developmental Biology pathway
REACT_111155
Cell-Cell communication pathway
REACT_20676
Cell junction organization pathway
REACT_21303
Myogenesis pathway
REACT_19331
Cell-cell junction organization pathway
KEGG
hsa04514
Cell adhesion molecules (CAMs) pathway
INOH
PID NCI
Cross-References
SwissProt P33146
TrEMBL
UniProt Splice Variant
Entrez Gene 12555
UniGene Mm.1976
RefSeq NM_007662
OMIM
CCDS CCDS22746
HPRD
IMGT
MGI ID MGI:106672
MGI Symbol Cdh15
EMBL AJ245402 BC157978 M74541
GenPept AAC23585 AAI57979 CAB57281
RNA Seq Atlas 12555

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca