Version 5.4
Mus musculus Gene: Tsen15
Summary
InnateDB Gene IDBG-198358.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Tsen15
Gene Name tRNA splicing endonuclease 15 homolog (S. cerevisiae)
Synonyms 5730449L18Rik; AL023077; Sen15
Species Mus musculus
Ensembl Gene ENSMUSG00000014980
Encoded Proteins
IDBP-198360
tRNA splicing endonuclease 15 homolog (S. cerevisiae)
IDBP-539812
tRNA splicing endonuclease 15 homolog (S. cerevisiae)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000198860:
tRNA splicing is a fundamental process required for cell growth and division. SEN15 is a subunit of the tRNA splicing endonuclease, which catalyzes the removal of introns, the first step in tRNA splicing (Paushkin et al., 2004 [PubMed 15109492]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 1:152370735-152386688
Strand Reverse strand
Band G2
Transcripts
ENSMUST00000015124 ENSMUSP00000015124
ENSMUST00000161717
ENSMUST00000162371 ENSMUSP00000124391
ENSMUST00000159270
ENSMUST00000159717
ENSMUST00000163027
ENSMUST00000188105
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 7 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000213 tRNA-intron endonuclease activity
GO:0003674 molecular_function
Biological Process
GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation
GO:0008150 biological_process
GO:0090502 RNA phosphodiester bond hydrolysis, endonucleolytic
Cellular Component
GO:0005575 cellular_component
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000198860
View Gene Order
ENSBTAG00000016369
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene
RefSeq NM_025677
OMIM
CCDS CCDS15363
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca