Version 5.4
| Mus musculus Gene: Disp2 | |||||||||||
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| Summary | |||||||||||
| InnateDB Gene | IDBG-198568.6 | ||||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||
| Gene Symbol | Disp2 | ||||||||||
| Gene Name | dispatched homolog 2 (Drosophila) | ||||||||||
| Synonyms | |||||||||||
| Species | Mus musculus | ||||||||||
| Ensembl Gene | ENSMUSG00000040035 | ||||||||||
| Encoded Proteins |
dispatched homolog 2 (Drosophila)
dispatched homolog 2 (Drosophila)
dispatched homolog 2 (Drosophila)
dispatched homolog 2 (Drosophila)
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| Protein Structure |
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| Useful resources | Stemformatics EHFPI ImmGen | ||||||||||
| Entrez Gene | |||||||||||
| Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000140323:
The pattern of cellular proliferation and differentiation that leads to normal development of embryonic structures often depends upon the localized production of secreted protein signals. Cells surrounding the source of a particular signal respond in a graded manner according to the effective concentration of the signal, and this response produces the pattern of cell types constituting the mature structure. A segment-polarity gene known as dispatched has been identified in Drosophila and its protein product is required for normal Hedgehog (Hh) signaling. This gene is one of two human homologs of Drosophila dispatched. [provided by RefSeq, Jul 2008] |
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| Gene Information | |||||||||||
| Type | Protein coding | ||||||||||
| Genomic Location | Chromosome 2:118779719-118811293 | ||||||||||
| Strand | Forward strand | ||||||||||
| Band | E5 | ||||||||||
| Transcripts |
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| Interactions | |||||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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| Gene Ontology | |||||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||||
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Species
Homo sapiens
Bos taurus
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Gene ID
Gene Order
Not yet available
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| Pathways | |||||||||||
| NETPATH | |||||||||||
| REACTOME |
Disease pathway
Hedgehog ligand biogenesis pathway
Processing-defective Hh variants abrogate ligand secretion pathway
Release of Hh-Np from the secreting cell pathway
Signaling by Hedgehog pathway
Signal Transduction pathway
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| KEGG | |||||||||||
| INOH |
Hedgehog signaling pathway pathway
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| PID NCI | |||||||||||
| Pathway Predictions based on Human Orthology Data | |||||||||||
| NETPATH | |||||||||||
| REACTOME |
Processing-defective Hh variants abrogate ligand secretion pathway
Signaling by Hedgehog pathway
Release of Hh-Np from the secreting cell pathway
Signal Transduction pathway
Hedgehog ligand biogenesis pathway
Disease pathway
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| KEGG | |||||||||||
| INOH | |||||||||||
| PID NCI | |||||||||||
| Cross-References | |||||||||||
| SwissProt | Q8CIP5 | ||||||||||
| TrEMBL | |||||||||||
| UniProt Splice Variant | |||||||||||
| Entrez Gene | 214240 | ||||||||||
| UniGene | Mm.221499 Mm.396798 Mm.401327 Mm.487505 | ||||||||||
| RefSeq | NM_170593 XM_006499107 | ||||||||||
| OMIM | |||||||||||
| CCDS | CCDS16584 | ||||||||||
| HPRD | |||||||||||
| IMGT | |||||||||||
| MGI ID | MGI:2388733 | ||||||||||
| MGI Symbol | Disp2 | ||||||||||
| EMBL | AK036480 AK122547 AL772255 AY150699 BC118526 | ||||||||||
| GenPept | AAI18527 AAN52162 BAC29446 BAC65829 CAM45999 CAM46000 | ||||||||||
| RNA Seq Atlas | 214240 | ||||||||||