Version 5.4
| Mus musculus Gene: Tubb3 | |||||||||||||||||||||||
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| Summary | |||||||||||||||||||||||
| InnateDB Gene | IDBG-199178.7 | ||||||||||||||||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||||||||||
| Gene Symbol | Tubb3 | ||||||||||||||||||||||
| Gene Name | tubulin, beta 3 class III | ||||||||||||||||||||||
| Synonyms | 3200002H15Rik; M(beta)3; M(beta)6 | ||||||||||||||||||||||
| Species | Mus musculus | ||||||||||||||||||||||
| Ensembl Gene | ENSMUSG00000062380 | ||||||||||||||||||||||
| Encoded Proteins |
tubulin, beta 3
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| Protein Structure | |||||||||||||||||||||||
| Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||||||||||
| Entrez Gene | |||||||||||||||||||||||
| Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000258947:
This gene encodes a class III member of the beta tubulin protein family. Beta tubulins are one of two core protein families (alpha and beta tubulins) that heterodimerize and assemble to form microtubules. This protein is primarily expressed in neurons and may be involved in neurogenesis and axon guidance and maintenance. Mutations in this gene are the cause of congenital fibrosis of the extraocular muscles type 3. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 6. [provided by RefSeq, Oct 2010] |
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| Gene Information | |||||||||||||||||||||||
| Type | Protein coding | ||||||||||||||||||||||
| Genomic Location | Chromosome 8:123411424-123422015 | ||||||||||||||||||||||
| Strand | Forward strand | ||||||||||||||||||||||
| Band | E1 | ||||||||||||||||||||||
| Transcripts |
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| Interactions | |||||||||||||||||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 24 experimentally validated interaction(s) in this database.
They are also associated with 49 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||||||||||||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||||||||||||||||
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Species
Homo sapiens
Bos taurus
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Gene ID
Gene Order
Not yet available
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| Pathways | |||||||||||||||||||||||
| NETPATH | |||||||||||||||||||||||
| REACTOME |
Recruitment of mitotic centrosome proteins and complexes pathway
Gap junction trafficking and regulation pathway
G2/M Transition pathway
Cell Cycle, Mitotic pathway
Hemostasis pathway
Separation of Sister Chromatids pathway
Recycling pathway of L1 pathway
Gap junction assembly pathway
Hedgehog 'off' state pathway
Resolution of Sister Chromatid Cohesion pathway
Membrane Trafficking pathway
Orphan transporters pathway
Chaperonin-mediated protein folding pathway
Cell Cycle pathway
Immune System pathway
M Phase pathway
Metabolism of proteins pathway
Recruitment of NuMA to mitotic centrosomes pathway
Post-chaperonin tubulin folding pathway pathway
Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane pathway
Kinesins pathway
Factors involved in megakaryocyte development and platelet production pathway
Mitotic G2-G2/M phases pathway
MHC class II antigen presentation pathway
Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding pathway
Protein folding pathway
Mitotic Metaphase and Anaphase pathway
Mitotic Prometaphase pathway
Axon guidance pathway
Transport of connexons to the plasma membrane pathway
Transmembrane transport of small molecules pathway
L1CAM interactions pathway
Adaptive Immune System pathway
Developmental Biology pathway
Signaling by Hedgehog pathway
Gap junction trafficking pathway
Signal Transduction pathway
Formation of tubulin folding intermediates by CCT/TriC pathway
Mitotic Anaphase pathway
Translocation of GLUT4 to the plasma membrane pathway
Prefoldin mediated transfer of substrate to CCT/TriC pathway
Centrosome maturation pathway
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| KEGG |
Gap junction pathway
Phagosome pathway
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| INOH | |||||||||||||||||||||||
| PID NCI | |||||||||||||||||||||||
| Pathway Predictions based on Human Orthology Data | |||||||||||||||||||||||
| NETPATH | |||||||||||||||||||||||
| REACTOME |
Resolution of Sister Chromatid Cohesion pathway
Mitotic Prometaphase pathway
Separation of Sister Chromatids pathway
Recruitment of NuMA to mitotic centrosomes pathway
Recruitment of mitotic centrosome proteins and complexes pathway
MHC class II antigen presentation pathway
Kinesins pathway
Factors involved in megakaryocyte development and platelet production pathway
Post-chaperonin tubulin folding pathway pathway
Prefoldin mediated transfer of substrate to CCT/TriC pathway
Formation of tubulin folding intermediates by CCT/TriC pathway
Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane pathway
Transport of connexons to the plasma membrane pathway
Gap junction assembly pathway
Translocation of GLUT4 to the plasma membrane pathway
Recycling pathway of L1 pathway
L1CAM interactions pathway
Protein folding pathway
Transmembrane transport of small molecules pathway
Developmental Biology pathway
Signaling by Hedgehog pathway
Axon guidance pathway
Signal Transduction pathway
Hedgehog 'off' state pathway
Gap junction trafficking pathway
Chaperonin-mediated protein folding pathway
Cell Cycle pathway
Orphan transporters pathway
Metabolism of proteins pathway
Adaptive Immune System pathway
Immune System pathway
Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding pathway
M Phase pathway
Mitotic Anaphase pathway
Centrosome maturation pathway
G2/M Transition pathway
Cell Cycle, Mitotic pathway
Mitotic G2-G2/M phases pathway
Gap junction trafficking and regulation pathway
Hemostasis pathway
Membrane Trafficking pathway
Mitotic Metaphase and Anaphase pathway
G2/M Transition pathway
Prefoldin mediated transfer of substrate to CCT/TriC pathway
Recycling pathway of L1 pathway
Factors involved in megakaryocyte development and platelet production pathway
M Phase pathway
L1CAM interactions pathway
Separation of Sister Chromatids pathway
Mitotic Metaphase and Anaphase pathway
Mitotic Anaphase pathway
Translocation of GLUT4 to the plasma membrane pathway
Hemostasis pathway
Immune System pathway
Cell Cycle, Mitotic pathway
Mitotic G2-G2/M phases pathway
Kinesins pathway
Gap junction trafficking pathway
Cell Cycle pathway
Signal Transduction pathway
Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding pathway
Gap junction assembly pathway
Chaperonin-mediated protein folding pathway
Hedgehog 'off' state pathway
Axon guidance pathway
MHC class II antigen presentation pathway
Metabolism of proteins pathway
Gap junction trafficking and regulation pathway
Recruitment of NuMA to mitotic centrosomes pathway
Protein folding pathway
Resolution of Sister Chromatid Cohesion pathway
Adaptive Immune System pathway
Signaling by Hedgehog pathway
Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane pathway
Recruitment of mitotic centrosome proteins and complexes pathway
Centrosome maturation pathway
Mitotic Prometaphase pathway
Transport of connexons to the plasma membrane pathway
Developmental Biology pathway
Formation of tubulin folding intermediates by CCT/TriC pathway
Membrane Trafficking pathway
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| KEGG |
Pathogenic Escherichia coli infection pathway
Gap junction pathway
Phagosome pathway
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| INOH | |||||||||||||||||||||||
| PID NCI | |||||||||||||||||||||||
| Cross-References | |||||||||||||||||||||||
| SwissProt | |||||||||||||||||||||||
| TrEMBL | |||||||||||||||||||||||
| UniProt Splice Variant | |||||||||||||||||||||||
| Entrez Gene | |||||||||||||||||||||||
| UniGene | Mm.40068 | ||||||||||||||||||||||
| RefSeq | NM_023279 | ||||||||||||||||||||||
| OMIM | |||||||||||||||||||||||
| CCDS | CCDS22757 | ||||||||||||||||||||||
| HPRD | |||||||||||||||||||||||
| IMGT | |||||||||||||||||||||||
| MGI ID | |||||||||||||||||||||||
| MGI Symbol | |||||||||||||||||||||||
| EMBL | |||||||||||||||||||||||
| GenPept | |||||||||||||||||||||||
| RNA Seq Atlas | |||||||||||||||||||||||