Version 5.4
Mus musculus Gene: Hnrpll
Summary
InnateDB Gene IDBG-199667.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Hnrpll
Gene Name heterogeneous nuclear ribonucleoprotein L-like
Synonyms 2510028H02Rik; 2810036L13Rik; AI256697; AI852082; Hnrpll
Species Mus musculus
Ensembl Gene ENSMUSG00000024095
Encoded Proteins
IDBP-199669
heterogeneous nuclear ribonucleoprotein L-like
IDBP-790558
heterogeneous nuclear ribonucleoprotein L-like
IDBP-790559
heterogeneous nuclear ribonucleoprotein L-like
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000143889:
HNRNPLL is a master regulator of activation-induced alternative splicing in T cells. In particular, it alters splicing of CD45 (PTPRC; MIM 151460), a tyrosine phosphatase essential for T-cell development and activation (Oberdoerffer et al., 2008 [PubMed 18669861]).[supplied by OMIM, Aug 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 17:80029487-80062334
Strand Reverse strand
Band E3
Transcripts
ENSMUST00000061331 ENSMUSP00000058308
ENSMUST00000184635 ENSMUSP00000139372
ENSMUST00000184297 ENSMUSP00000139075
ENSMUST00000183516
ENSMUST00000184578
ENSMUST00000184889
ENSMUST00000184726
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 11 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 11 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0003676 nucleic acid binding
GO:0003723 RNA binding
GO:0003729 mRNA binding
GO:0005515 protein binding
GO:0044822 poly(A) RNA binding
Biological Process
GO:0006397 mRNA processing
GO:0033120 positive regulation of RNA splicing
Cellular Component
GO:0005634 nucleus
GO:0016020 membrane
GO:0030529 ribonucleoprotein complex
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000143889
View Gene Order
ENSBTAG00000020567
Not yet available
Cross-References
SwissProt Q921F4
TrEMBL V9GXB6
UniProt Splice Variant
Entrez Gene 72692
UniGene
RefSeq NM_144802
OMIM
CCDS CCDS70845
HPRD
IMGT
MGI ID MGI:1919942
MGI Symbol Hnrnpll
EMBL AC122253 AK034860 AK146879 BC004763 BC012849 BC071184
GenPept AAH04763 AAH12849 AAH71184 BAC28858 BAE27500
RNA Seq Atlas 72692

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca