Version 5.4
Mus musculus Gene: Cep350
Summary
InnateDB Gene IDBG-199985.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Cep350
Gene Name centrosomal protein 350
Synonyms 4933409L06Rik; 6430546F08Rik
Species Mus musculus
Ensembl Gene ENSMUSG00000033671
Encoded Proteins
IDBP-540797
centrosomal protein 350
IDBP-537165
centrosomal protein 350
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000135837:
The product of this gene is a large protein with a CAP-Gly domain typically found in cytoskeleton-associated proteins. The encoded protein primarily localizes to the centrosome, a non-membraneous organelle that functions as the major microtubule-organizing center in animal cells. The encoded protein directly interacts with another large centrosomal protein and is required to anchor microtubules at the centrosome. It is also implicated in the regulation of a class of nuclear hormone receptors in the nucleus. Several alternatively spliced transcript variants have been found, but their full-length nature has not been determined. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 1:155844966-155972890
Strand Reverse strand
Band G3
Transcripts
ENSMUST00000138762 ENSMUSP00000120085
ENSMUST00000132189
ENSMUST00000137330
ENSMUST00000129865
ENSMUST00000146987
ENSMUST00000124495 ENSMUSP00000121043
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 12 experimentally validated interaction(s) in this database.
They are also associated with 8 interaction(s) predicted by orthology.
Experimentally validated
Total 12 [view]
Protein-Protein 12 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 8 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0008017 microtubule binding
Biological Process
GO:0008150 biological_process
GO:0034453 microtubule anchoring
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005813 centrosome
GO:0016020 membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000135837
View Gene Order
ENSBTAG00000008082
Not yet available
Cross-References
SwissProt
TrEMBL D3YTP2 E9Q309 Q8BXM7
UniProt Splice Variant
Entrez Gene 74081
UniGene Mm.260247 Mm.412799
RefSeq NM_001039184 XM_006529905 XM_006529906 XM_006529907
OMIM
CCDS CCDS48400
HPRD
IMGT
MGI ID MGI:1921331
MGI Symbol Cep350
EMBL AC120391 AC121314 AK044664
GenPept BAC32024
RNA Seq Atlas 74081

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca