Version 5.4
Mus musculus Gene: Cog2
Summary
InnateDB Gene IDBG-200083.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Cog2
Gene Name component of oligomeric golgi complex 2
Synonyms 1190002B08Rik; 2700012E02Rik; C86089; Ldlc
Species Mus musculus
Ensembl Gene ENSMUSG00000031979
Encoded Proteins
IDBP-200085
component of oligomeric golgi complex 2
IDBP-716089
IDBP-717943
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000135775:
This gene encodes a subunit of the conserved oligomeric Golgi complex that is required for maintaining normal structure and activity of the Golgi complex. The encoded protein specifically interacts with the USO1 vesicle docking protein and may be necessary for normal Golgi ribbon formation and trafficking of Golgi enzymes. Mutations of this gene are associated with abnormal glycosylation within the Golgi apparatus. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Feb 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 8:124520767-124552008
Strand Forward strand
Band E2
Transcripts
ENSMUST00000034460 ENSMUSP00000034460
ENSMUST00000108803
ENSMUST00000129977
ENSMUST00000176159 ENSMUSP00000135600
ENSMUST00000176279 ENSMUSP00000135022
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 9 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 9 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0008565 protein transporter activity
GO:0032403 protein complex binding
Biological Process
GO:0006891 intra-Golgi vesicle-mediated transport
GO:0007030 Golgi organization
GO:0015031 protein transport
Cellular Component
GO:0000139 Golgi membrane
GO:0005795 Golgi stack
GO:0005829 cytosol
GO:0016020 membrane
GO:0017119 Golgi transport complex
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000135775
View Gene Order
ENSBTAG00000020314
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.240108 Mm.395742 Mm.489549
RefSeq NM_029746 XM_006531473
OMIM
CCDS CCDS22771
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca