Version 5.4
Mus musculus Gene: Ak5
Summary
InnateDB Gene IDBG-200335.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Ak5
Gene Name adenylate kinase 5
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000039058
Encoded Proteins
IDBP-200337
adenylate kinase 5
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000154027:
This gene encodes a member of the adenylate kinase family, which is involved in regulating the adenine nucleotide composition within a cell by catalyzing the reversible transfer of phosphate groups among adenine nucleotides. This member is related to the UMP/CMP kinase of several species. It is located in the cytosol and expressed exclusively in brain. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 3:152462815-152668140
Strand Reverse strand
Band H3
Transcripts
ENSMUST00000045262 ENSMUSP00000042785
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 9 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 9 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004017 adenylate kinase activity
GO:0004550 nucleoside diphosphate kinase activity
GO:0005524 ATP binding
GO:0019206 nucleoside kinase activity
Biological Process
GO:0006165 nucleoside diphosphate phosphorylation
GO:0009142 nucleoside triphosphate biosynthetic process
GO:0046034 ATP metabolic process
Cellular Component
GO:0005737 cytoplasm
GO:0005813 centrosome
GO:0005815 microtubule organizing center
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000154027
View Gene Order
ENSBTAG00000017411
Not yet available
Pathways
NETPATH
REACTOME
REACT_238368
Synthesis and interconversion of nucleotide di- and triphosphates pathway
REACT_188937
Metabolism pathway
REACT_245662
Metabolism of nucleotides pathway
KEGG
mmu00230
Purine metabolism pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_21330
Synthesis and interconversion of nucleotide di- and triphosphates pathway
REACT_1698
Metabolism of nucleotides pathway
REACT_111217
Metabolism pathway
REACT_210940
Metabolism of nucleotides pathway
REACT_219139
Metabolism pathway
REACT_223832
Synthesis and interconversion of nucleotide di- and triphosphates pathway
KEGG
hsa00230
Purine metabolism pathway
INOH
INOH website
Purine nucleotides nucleosides metabolism pathway
PID NCI
Cross-References
SwissProt Q920P5
TrEMBL
UniProt Splice Variant
Entrez Gene 229949
UniGene Mm.207057
RefSeq NM_001081277 XM_006501440
OMIM
CCDS CCDS38675
HPRD
IMGT
MGI ID MGI:2677491
MGI Symbol Ak5
EMBL AB060081 AC111139 AC116720 AK053807
GenPept BAB69859
RNA Seq Atlas 229949

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca