InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Gene: Snrnp35

Summary

InnateDB Gene

IDBG-200705.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Snrnp35

Gene Name

small nuclear ribonucleoprotein 35 (U11/U12)

Synonyms

6330548G22Rik

Species

Mus musculus

Ensembl Gene

ENSMUSG00000029402

Encoded Proteins

IDBP-200707

small nuclear ribonucleoprotein 35 (U11/U12)

IDBP-258088

small nuclear ribonucleoprotein 35 (U11/U12)

IDBP-537417

small nuclear ribonucleoprotein 35 (U11/U12)

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000184209:
The protein encoded by this gene is a homolog of U1-snRNP binding protein. The N-terminal half contains a RNA recognition motif and the C-terminal is rich in Arg/Asp and Arg/Glu dipeptides; a characteristic of a variety of splicing factors. This protein is a component of the U11/U12 small nuclear ribonucleoproteins (snRNP) that form part of the U12-type spliceosome. This gene is differentially expressed in a variety of human tissues. Alternative splicing results in multiple transcript variants encoding distinct proteins.[provided by RefSeq, Nov 2008]
The protein encoded by this gene is a homolog of the U1-snRNP binding protein. The N-terminal half contains a RNA recognition motif and the C-terminal half is rich in Arg/Asp and Arg/Glu dipeptides, which is a characteristic of a variety of splicing factors. This protein is a component of the U11/U12 small nuclear ribonucleoproteins (snRNP) that form part of the U12-type spliceosome. Alternative splicing results in multiple transcript variants encoding two distinct isoforms and representing a non-protein coding variant. [provided by RefSeq, Aug 2013]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 5:124483134-124491124

Strand

Forward strand

Band

Transcripts

ENSMUST00000031349	ENSMUSP00000031349
ENSMUST00000111453	ENSMUSP00000107080
ENSMUST00000136567	ENSMUSP00000121120

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.

Experimentally validated
Total	1 [view]
Protein-Protein	0
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	6 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000166	nucleotide binding
GO:0003674	molecular_function
GO:0003676	nucleic acid binding
GO:0003723	RNA binding

Biological Process

GO:0006397	mRNA processing
GO:0008150	biological_process
GO:0008380	RNA splicing

Cellular Component

GO:0005634	nucleus
GO:0005689	U12-type spliceosomal complex

Orthologs

Species

Homo sapiens

Bos taurus

Gene ID

Gene Order

ENSG00000184209

View Gene Order

ENSBTAG00000008060

Not yet available

Cross-References

SwissProt

Q9D384

TrEMBL

D3YTL6

UniProt Splice Variant

Entrez Gene

76167

UniGene

Mm.156035

RefSeq

NM_029532 XM_006530495 XM_006530494

OMIM

CCDS

CCDS19677

HPRD

IMGT

MGI ID

MGI:1923417

MGI Symbol

Snrnp35

EMBL

AC127313 AK018232 AK039064 BC043031 BC058361

GenPept

AAH43031 AAH58361 BAB31127 BAC30228

RNA Seq Atlas

76167