Version 5.4
Mus musculus Gene: Tmed2
Summary
InnateDB Gene IDBG-200723.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Tmed2
Gene Name transmembrane emp24 domain trafficking protein 2
Synonyms 1110032D12Rik; 1810020N21Rik; p24beta1; Rnp24; Sid394
Species Mus musculus
Ensembl Gene ENSMUSG00000029390
Encoded Proteins
IDBP-200725
transmembrane emp24 domain trafficking protein 2
IDBP-537808
transmembrane emp24 domain trafficking protein 2
IDBP-537990
transmembrane emp24 domain trafficking protein 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000086598:
Gene Information
Type Protein coding
Genomic Location Chromosome 5:124540695-124550506
Strand Forward strand
Band F
Transcripts
ENSMUST00000060226 ENSMUSP00000054834
ENSMUST00000124529 ENSMUSP00000115169
ENSMUST00000135464 ENSMUSP00000120809
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 29 interaction(s) predicted by orthology.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 29 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0001893 maternal placenta development
GO:0006810 transport
GO:0006886 intracellular protein transport
GO:0007030 Golgi organization
GO:0016192 vesicle-mediated transport
GO:0034260 negative regulation of GTPase activity
GO:0048598 embryonic morphogenesis
GO:0072661 protein targeting to plasma membrane
Cellular Component
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0005793 endoplasmic reticulum-Golgi intermediate compartment
GO:0005794 Golgi apparatus
GO:0016021 integral component of membrane
GO:0030137 COPI-coated vesicle
GO:0030663 COPI-coated vesicle membrane
GO:0032580 Golgi cisterna membrane
GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane
GO:0042589 zymogen granule membrane
GO:0043231 intracellular membrane-bounded organelle
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000086598
View Gene Order
ENSBTAG00000039630
Not yet available
Pathways
NETPATH
REACTOME
REACT_196494
Pre-NOTCH Expression and Processing pathway
REACT_196517
Pre-NOTCH Processing in Golgi pathway
REACT_188257
Signal Transduction pathway
REACT_231152
Signaling by NOTCH pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_118798
Pre-NOTCH Processing in Golgi pathway
REACT_118744
Pre-NOTCH Expression and Processing pathway
REACT_111102
Signal Transduction pathway
REACT_299
Signaling by NOTCH pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt Q9R0Q3
TrEMBL A2RS53 Q3THL1 Q3U9H7 Q8BPI2 Q8C1Z9
UniProt Splice Variant
Entrez Gene 56334
UniGene Mm.325255 Mm.352870 Mm.423608 Mm.425279 Mm.483273
RefSeq NM_019770 XM_003945446
OMIM
CCDS CCDS19679
HPRD
IMGT
MGI ID MGI:1929269
MGI Symbol Tmed2
EMBL AB025218 AC127313 AK075642 AK089965 AK150560 AK151788 AK168235 BC083140 BC131977 BC138294 CH466529
GenPept AAH83140 AAI31978 AAI38295 BAA84689 BAC35876 BAC41019 BAE29659 BAE30689 BAE40185 EDL19580
RNA Seq Atlas 100862175 56334

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca