Mus musculus Gene: Ganc
Summary
InnateDB Gene IDBG-200841.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Ganc
Gene Name glucosidase, alpha; neutral C
Synonyms 5830445O15Rik; 9330160A12; mFLJ00088
Species Mus musculus
Ensembl Gene ENSMUSG00000062646
Encoded Proteins
glucosidase, alpha; neutral C
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000214013:
Glycosyl hydrolase enzymes hydrolyse the glycosidic bond between two or more carbohydrates, or between a carbohydrate and a non-carbohydrate moiety. This gene encodes a member of glycosyl hydrolases family 31. This enzyme hydrolyses terminal, non-reducing 1,4-linked alpha-D-glucose residues and releases alpha-D-glucose. This is a key enzyme in glycogen metabolism and its gene localizes to a chromosomal region (15q15) that is associated with susceptibility to diabetes. [provided by RefSeq, Jul 2008]
Glycosyl hydrolase enzymes hydrolyse the glycosidic bond between two or more carbohydrates, or between a carbohydrate and a non-carbohydrate moiety. This gene encodes a member of glycosyl hydrolases family 31. This enzyme hydrolyses terminal, non-reducing 1,4-linked alpha-D-glucose residues and releases alpha-D-glucose. This is a key enzyme in glycogen metabolism and its gene localizes to a chromosomal region (15q15) that is associated with susceptibility to diabetes. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Aug 2014]
Gene Information
Type Protein coding
Genomic Location Chromosome 2:120403896-120461700
Strand Forward strand
Band E5
Transcripts
ENSMUST00000043755
ENSMUST00000154574
ENSMUST00000154963
ENSMUST00000131523
ENSMUST00000153660
ENSMUST00000154404
ENSMUST00000143409
ENSMUST00000135074 ENSMUSP00000116898
ENSMUST00000154435
ENSMUST00000136993
ENSMUST00000152437
ENSMUST00000132835
ENSMUST00000145134
ENSMUST00000127367
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003824 catalytic activity
GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds
GO:0004558 alpha-glucosidase activity
GO:0030246 carbohydrate binding
Biological Process
GO:0005975 carbohydrate metabolic process
GO:0006006 glucose metabolic process
Cellular Component
GO:0005575 cellular_component
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Not yet available
Pathways
NETPATH
REACTOME
KEGG
Starch and sucrose metabolism pathway
Galactose metabolism pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
Galactose metabolism pathway
Starch and sucrose metabolism pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.38851 Mm.410342 Mm.440665
RefSeq NM_172672
OMIM
CCDS CCDS38211
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas