Version 5.4
Mus musculus Gene: Arhgef10l
Summary
InnateDB Gene IDBG-201081.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Arhgef10l
Gene Name Rho guanine nucleotide exchange factor (GEF) 10-like
Synonyms 2810441C07Rik
Species Mus musculus
Ensembl Gene ENSMUSG00000040964
Encoded Proteins
IDBP-201083
Rho guanine nucleotide exchange factor (GEF) 10-like
IDBP-201085
Rho guanine nucleotide exchange factor (GEF) 10-like
IDBP-201087
Rho guanine nucleotide exchange factor (GEF) 10-like
IDBP-270101
Rho guanine nucleotide exchange factor (GEF) 10-like
IDBP-270103
Rho guanine nucleotide exchange factor (GEF) 10-like
IDBP-270105
Rho guanine nucleotide exchange factor (GEF) 10-like
IDBP-533487
Rho guanine nucleotide exchange factor (GEF) 10-like
IDBP-539331
Rho guanine nucleotide exchange factor (GEF) 10-like
IDBP-534889
Rho guanine nucleotide exchange factor (GEF) 10-like
IDBP-535434
Rho guanine nucleotide exchange factor (GEF) 10-like
IDBP-539320
Rho guanine nucleotide exchange factor (GEF) 10-like
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000074964:
ARHGEF10L is a member of the RhoGEF family of guanine nucleotide exchange factors (GEFs) that activate Rho GTPases (Winkler et al., 2005 [PubMed 16112081]).[supplied by OMIM, Dec 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 4:140514485-140666012
Strand Reverse strand
Band D3
Transcripts
ENSMUST00000039204 ENSMUSP00000040531
ENSMUST00000097820 ENSMUSP00000095431
ENSMUST00000069623 ENSMUSP00000066249
ENSMUST00000105799 ENSMUSP00000101425
ENSMUST00000105798 ENSMUSP00000101424
ENSMUST00000105797 ENSMUSP00000101423
ENSMUST00000138493 ENSMUSP00000119471
ENSMUST00000140403 ENSMUSP00000117038
ENSMUST00000147426 ENSMUSP00000123642
ENSMUST00000125045
ENSMUST00000143614 ENSMUSP00000120437
ENSMUST00000154979 ENSMUSP00000122667
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005089 Rho guanyl-nucleotide exchange factor activity
GO:0005515 protein binding
Biological Process
GO:0032319 regulation of Rho GTPase activity
GO:0035023 regulation of Rho protein signal transduction
Cellular Component
GO:0005737 cytoplasm
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000074964
View Gene Order
ENSBTAG00000000684
Not yet available
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
INOH
PID NCI
rhoa_reg_pathway
Regulation of RhoA activity
Cross-References
SwissProt
TrEMBL A2AWP4
UniProt Splice Variant
Entrez Gene 72754
UniGene Mm.29329
RefSeq NM_001112722 NM_001112723 NM_001290803 NM_172415 XM_006539201 XM_006539202 XM_006539203 XM_006539204
OMIM
CCDS CCDS51342 CCDS51343 CCDS51344 CCDS71507
HPRD
IMGT
MGI ID MGI:1920004
MGI Symbol Arhgef10l
EMBL AL929073 AL954710 BX530090
GenPept
RNA Seq Atlas 72754

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca