Version 5.4
Mus musculus Gene: Cript
Summary
InnateDB Gene IDBG-201327.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Cript
Gene Name cysteine-rich PDZ-binding protein
Synonyms 1200020A08Rik; AA589469
Species Mus musculus
Ensembl Gene ENSMUSG00000024146
Encoded Proteins
IDBP-201329
cysteine-rich PDZ-binding protein
IDBP-532713
cysteine-rich PDZ-binding protein
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000119878:
This gene encodes a protein that binds to the PDZ3 peptide recognition domain. The encoded protein may modulates protein interactions with the cytoskeleton. A mutation in this gene resulted in short stature with microcephaly and distinctive facies. [provided by RefSeq, Jun 2014]
Gene Information
Type Protein coding
Genomic Location Chromosome 17:87025550-87035810
Strand Forward strand
Band E4
Transcripts
ENSMUST00000024959 ENSMUSP00000024959
ENSMUST00000160824
ENSMUST00000160269 ENSMUSP00000124994
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 1 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 6 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0008017 microtubule binding
GO:0030165 PDZ domain binding
GO:0032403 protein complex binding
Biological Process
GO:0031122 cytoplasmic microtubule organization
GO:0035372 protein localization to microtubule
GO:0045184 establishment of protein localization
GO:1902897 regulation of postsynaptic density protein 95 clustering
Cellular Component
GO:0005737 cytoplasm
GO:0014069 postsynaptic density
GO:0030054 cell junction
GO:0030425 dendrite
GO:0043025 neuronal cell body
GO:0043197 dendritic spine
GO:0043198 dendritic shaft
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000119878
View Gene Order
ENSBTAG00000015723
Not yet available
Cross-References
SwissProt
TrEMBL F6TQQ9
UniProt Splice Variant
Entrez Gene 56724
UniGene Mm.473232
RefSeq NM_019936
OMIM
CCDS CCDS29012
HPRD
IMGT
MGI ID MGI:1929655
MGI Symbol Cript
EMBL AC127695
GenPept
RNA Seq Atlas 56724

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca