Version 5.4
Mus musculus Gene: Relt
Summary
InnateDB Gene IDBG-201680.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Relt
Gene Name RELT tumor necrosis factor receptor
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000008318
Encoded Proteins
IDBP-201682
RELT tumor necrosis factor receptor
IDBP-541967
RELT tumor necrosis factor receptor
IDBP-539310
RELT tumor necrosis factor receptor
IDBP-532994
RELT tumor necrosis factor receptor
IDBP-539530
RELT tumor necrosis factor receptor
IDBP-535609
RELT tumor necrosis factor receptor
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000054967:
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is especially abundant in hematologic tissues. It has been shown to activate the NF-kappaB pathway and selectively bind TNF receptor-associated factor 1 (TRAF1). This receptor is capable of stimulating T-cell proliferation in the presence of CD3 signaling, which suggests its regulatory role in immune response. Two alternatively spliced transcript variants of this gene encoding the same protein have been reported. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 7:100845848-100863446
Strand Reverse strand
Band E2
Transcripts
ENSMUST00000008462 ENSMUSP00000008462
ENSMUST00000155413 ENSMUSP00000118150
ENSMUST00000156855 ENSMUSP00000120042
ENSMUST00000139604 ENSMUSP00000119208
ENSMUST00000136231 ENSMUSP00000121443
ENSMUST00000142885 ENSMUSP00000121049
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0005515 protein binding
Biological Process
GO:0012501 programmed cell death
Cellular Component
GO:0005575 cellular_component
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:0016021 integral component of membrane
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000054967
View Gene Order
ENSBTAG00000016494
Not yet available
Pathways
NETPATH
REACTOME
KEGG
mmu04060
Cytokine-cytokine receptor interaction pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
hsa04060
Cytokine-cytokine receptor interaction pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL D3Z306
UniProt Splice Variant
Entrez Gene 320100
UniGene Mm.40336 Mm.466525
RefSeq NM_177073 XM_006507931 XM_006507932 XM_006507933 XM_006507934 XM_006507935 XM_006507936 XM_006507937 XM_006507938
OMIM
CCDS CCDS21506
HPRD
IMGT
MGI ID MGI:2443373
MGI Symbol Relt
EMBL AC150744
GenPept
RNA Seq Atlas 320100

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca