Version 5.4
Mus musculus Gene: Pigs
Summary
InnateDB Gene IDBG-202717.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Pigs
Gene Name phosphatidylinositol glycan anchor biosynthesis, class S
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000041958
Encoded Proteins
IDBP-202719
phosphatidylinositol glycan anchor biosynthesis, class S
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000087111:
This gene encodes a protein that is involved in GPI-anchor biosynthesis. The glycosylphosphatidylinositol (GPI) anchor is a glycolipid found on many blood cells and serves to anchor proteins to the cell surface. This gene encodes an essential component of the multisubunit enzyme, GPI transamidase. GPI transamidase mediates GPI anchoring in the endoplasmic reticulum, by catalyzing the transfer of fully assembled GPI units to proteins. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 11:78328415-78342782
Strand Forward strand
Band B5
Transcripts
ENSMUST00000048073 ENSMUSP00000044871
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 12 interaction(s) predicted by orthology.
Predicted by orthology
Total 12 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003923 GPI-anchor transamidase activity
GO:0005515 protein binding
Biological Process
GO:0016255 attachment of GPI anchor to protein
Cellular Component
GO:0005575 cellular_component
GO:0016020 membrane
GO:0042765 GPI-anchor transamidase complex
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000087111
View Gene Order
ENSBTAG00000013098
Not yet available
Pathways
NETPATH
REACTOME
REACT_244576
Post-translational modification: synthesis of GPI-anchored proteins pathway
REACT_247926
Metabolism of proteins pathway
REACT_236283
Post-translational protein modification pathway
REACT_236590
Attachment of GPI anchor to uPAR pathway
KEGG
mmu00563
Glycosylphosphatidylinositol(GPI)-anchor biosynthesis pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_1830
Attachment of GPI anchor to uPAR pathway
REACT_1853
Post-translational modification: synthesis of GPI-anchored proteins pathway
REACT_22161
Post-translational protein modification pathway
REACT_17015
Metabolism of proteins pathway
KEGG
hsa00563
Glycosylphosphatidylinositol(GPI)-anchor biosynthesis pathway
INOH
PID NCI
Cross-References
SwissProt Q6PD26
TrEMBL Q3V307
UniProt Splice Variant
Entrez Gene 276846
UniGene Mm.415815
RefSeq NM_201406 XM_006533471
OMIM
CCDS CCDS25100
HPRD
IMGT
MGI ID MGI:2687325
MGI Symbol Pigs
EMBL AK033331 AK053771 AK151858 AK152229 AL591070 BC058979 CH466556
GenPept AAH58979 BAE20485 BAE20693 BAE30747 BAE31056 CAI24317 EDL15565
RNA Seq Atlas 276846

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca