InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Gene: Baz1b

Summary

InnateDB Gene

IDBG-203632.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Baz1b

Gene Name

bromodomain adjacent to zinc finger domain, 1B

Synonyms

C87820; Wbscr9; WSTF

Species

Mus musculus

Ensembl Gene

ENSMUSG00000002748

Encoded Proteins

IDBP-203634

bromodomain adjacent to zinc finger domain, 1B

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000009954:
This gene encodes a member of the bromodomain protein family. The bromodomain is a structural motif characteristic of proteins involved in chromatin-dependent regulation of transcription. This gene is deleted in Williams-Beuren syndrome, a developmental disorder caused by deletion of multiple genes at 7q11.23. [provided by RefSeq, Jul 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 5:135187264-135246129

Strand

Forward strand

Band

Transcripts

ENSMUST00000002825	ENSMUSP00000002825
ENSMUST00000142307
ENSMUST00000136947
ENSMUST00000176793

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 25 experimentally validated interaction(s) in this database.
They are also associated with 43 interaction(s) predicted by orthology.

Experimentally validated
Total	25 [view]
Protein-Protein	25 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	43 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003682	chromatin binding
GO:0004713	protein tyrosine kinase activity
GO:0004715	non-membrane spanning protein tyrosine kinase activity
GO:0005515	protein binding
GO:0005524	ATP binding
GO:0008270	zinc ion binding
GO:0032947	protein complex scaffold
GO:0035173	histone kinase activity
GO:0042393	histone binding
GO:0042809	vitamin D receptor binding
GO:0070577	lysine-acetylated histone binding
GO:0071884	vitamin D receptor activator activity

Biological Process

GO:0003007	heart morphogenesis
GO:0006302	double-strand break repair
GO:0006333	chromatin assembly or disassembly
GO:0006338	chromatin remodeling
GO:0006351	transcription, DNA-templated
GO:0006355	regulation of transcription, DNA-templated
GO:0006974	cellular response to DNA damage stimulus
GO:0016572	histone phosphorylation
GO:0018108	peptidyl-tyrosine phosphorylation
GO:0034725	DNA replication-dependent nucleosome disassembly
GO:0043044	ATP-dependent chromatin remodeling
GO:0048096	chromatin-mediated maintenance of transcription
GO:2000273	positive regulation of receptor activity

Cellular Component

GO:0000793	condensed chromosome
GO:0005634	nucleus
GO:0005721	centromeric heterochromatin
GO:0043596	nuclear replication fork
GO:0071778	WINAC complex

Orthologs

Species

Homo sapiens

Bos taurus

Gene ID

Gene Order

ENSG00000009954

View Gene Order

ENSBTAG00000005197

Not yet available

Pathway Predictions based on Human Orthology Data

NETPATH

REACTOME

KEGG

INOH

PID NCI

Cross-References

SwissProt

Q9Z277

TrEMBL

UniProt Splice Variant

Entrez Gene

22385

UniGene

Mm.40331 Mm.413272 Mm.473791

RefSeq

NM_011714

OMIM

CCDS

CCDS19736

HPRD

IMGT

MGI ID

MGI:1353499

MGI Symbol

Baz1b

EMBL

AF084480 AK017894 AK037737 AK137139 AK140172 AK141305 BC141399 CH466529

GenPept

AAD08676 AAI41400 BAB30992 BAC29862 BAE23247 BAE24264 BAE24643 EDL19376

RNA Seq Atlas

22385