Version 5.4
Mus musculus Gene: Ccl7
Summary
InnateDB Gene IDBG-204496.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Ccl7
Gene Name chemokine (C-C motif) ligand 7
Synonyms fic; marc; MCP-3; mcp3; Scya7
Species Mus musculus
Ensembl Gene ENSMUSG00000035373
Encoded Proteins
IDBP-204498
chemokine (C-C motif) ligand 7
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 11:82045712-82047525
Strand Forward strand
Band C
Transcripts
ENSMUST00000021011 ENSMUSP00000021011
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
Experimentally validated
Total 4 [view]
Protein-Protein 2 [view]
Protein-DNA 2 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0008009 chemokine activity
GO:0008201 heparin binding
GO:0031726 CCR1 chemokine receptor binding
GO:0031727 CCR2 chemokine receptor binding
Biological Process
GO:0006954 inflammatory response
GO:0006955 immune response
GO:0007010 cytoskeleton organization
GO:0008360 regulation of cell shape
GO:0010332 response to gamma radiation
GO:0030335 positive regulation of cell migration
GO:0048245 eosinophil chemotaxis
GO:0071361 cellular response to ethanol
GO:2000503 positive regulation of natural killer cell chemotaxis
Cellular Component
GO:0005576 extracellular region
GO:0005615 extracellular space
Orthologs
No orthologs found for this gene
Pathways
NETPATH
REACTOME
REACT_254215
Signaling by GPCR pathway
REACT_261161
Class A/1 (Rhodopsin-like receptors) pathway
REACT_231468
GPCR ligand binding pathway
REACT_235286
Peptide ligand-binding receptors pathway
REACT_230248
Chemokine receptors bind chemokines pathway
REACT_188257
Signal Transduction pathway
KEGG
mmu04060
Cytokine-cytokine receptor interaction pathway
mmu04062
Chemokine signaling pathway pathway
INOH
PID NCI
Cross-References
SwissProt Q03366
TrEMBL A9Z1Z1
UniProt Splice Variant
Entrez Gene 20306
UniGene Mm.341574
RefSeq NM_013654
OMIM
CCDS CCDS36245
HPRD
IMGT
MGI ID MGI:99512
MGI Symbol Ccl7
EMBL AF128193 AF128194 AK078827 BC061126 CH466556 L04694 S50588 S71251 X70058 Z12297
GenPept AAA12542 AAA37516 AAB30997 AAF22534 AAF22535 AAH61126 BAC37413 CAA49662 CAA78169 EDL15658
RNA Seq Atlas 20306

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca