Version 5.4
Mus musculus Gene: Blvra
Summary
InnateDB Gene IDBG-204542.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Blvra
Gene Name biliverdin reductase A
Synonyms 0610006A11Rik; 2500001N03Rik; Blvr
Species Mus musculus
Ensembl Gene ENSMUSG00000001999
Encoded Proteins
IDBP-204546
biliverdin reductase A
IDBP-260377
biliverdin reductase A
IDBP-537960
biliverdin reductase A
IDBP-532736
biliverdin reductase A
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000106605:
The protein encoded by this gene belongs to the biliverdin reductase family, members of which catalyze the conversion of biliverdin to bilirubin in the presence of NADPH or NADH. Mutations in this gene are associated with hyperbiliverdinemia. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Dec 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 2:127070665-127097084
Strand Forward strand
Band F1
Transcripts
ENSMUST00000002064 ENSMUSP00000002064
ENSMUST00000110389 ENSMUSP00000106019
ENSMUST00000142861
ENSMUST00000135529 ENSMUSP00000118278
ENSMUST00000142737 ENSMUSP00000116825
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 7 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0004074 biliverdin reductase activity
GO:0008270 zinc ion binding
GO:0016491 oxidoreductase activity
GO:0050661 NADP binding
Biological Process
GO:0042167 heme catabolic process
GO:0055114 oxidation-reduction process
Cellular Component
GO:0005737 cytoplasm
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000106605
View Gene Order
ENSBTAG00000013414
Not yet available
Pathways
NETPATH
REACTOME
REACT_188937
Metabolism pathway
REACT_233393
Heme degradation pathway
REACT_233360
Metabolism of porphyrins pathway
KEGG
mmu00860
Porphyrin and chlorophyll metabolism pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_22297
Heme degradation pathway
REACT_9431
Metabolism of porphyrins pathway
REACT_111217
Metabolism pathway
KEGG
hsa00860
Porphyrin and chlorophyll metabolism pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.22028
RefSeq NM_026678 XM_006498569 XM_006498570 XM_006498571 XM_006498572
OMIM
CCDS CCDS16692
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca