InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Gene: Ap1s1

Summary

InnateDB Gene

IDBG-204780.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Ap1s1

Gene Name

adaptor protein complex AP-1, sigma 1

Synonyms

AP19

Species

Mus musculus

Ensembl Gene

ENSMUSG00000004849

Encoded Proteins

IDBP-258882

adaptor protein complex AP-1, sigma 1

IDBP-536867

adaptor protein complex AP-1, sigma 1

IDBP-537613

adaptor protein complex AP-1, sigma 1

IDBP-536134

adaptor protein complex AP-1, sigma 1

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000106367:
The protein encoded by this gene is part of the clathrin coat assembly complex which links clathrin to receptors in coated vesicles. These vesicles are involved in endocytosis and Golgi processing. This protein, as well as beta-prime-adaptin, gamma-adaptin, and the medium (mu) chain AP47, form the AP-1 assembly protein complex located at the Golgi vesicle. [provided by RefSeq, Jul 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 5:137034993-137046135

Strand

Reverse strand

Band

Transcripts

ENSMUST00000111080	ENSMUSP00000106709
ENSMUST00000154183
ENSMUST00000150603	ENSMUSP00000115941
ENSMUST00000144303	ENSMUSP00000120895
ENSMUST00000129356	ENSMUSP00000119458

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 11 interaction(s) predicted by orthology.

Experimentally validated
Total	2 [view]
Protein-Protein	2 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	11 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0008565	protein transporter activity

Biological Process

GO:0006810	transport
GO:0006886	intracellular protein transport
GO:0009615	response to virus
GO:0015031	protein transport
GO:0016192	vesicle-mediated transport

Cellular Component

GO:0005802	trans-Golgi network
GO:0005905	coated pit
GO:0016020	membrane
GO:0030117	membrane coat
GO:0030121	AP-1 adaptor complex
GO:0070062	extracellular vesicular exosome