Homo sapiens Gene: MRPS25
Summary
InnateDB Gene IDBG-20508.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MRPS25
Gene Name mitochondrial ribosomal protein S25
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000131368
Encoded Proteins
mitochondrial ribosomal protein S25
mitochondrial ribosomal protein S25
mitochondrial ribosomal protein S25
mitochondrial ribosomal protein S25
mitochondrial ribosomal protein S25
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein. A pseudogene corresponding to this gene is found on chromosome 4. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 3:15042460-15065335
Strand Reverse strand
Band p25.1
Transcripts
ENST00000253686 ENSP00000253686
ENST00000449354 ENSP00000390882
ENST00000420267 ENSP00000396828
ENST00000444840 ENSP00000407733
ENST00000447299 ENSP00000402068
ENST00000496484
ENST00000474866
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 20 experimentally validated interaction(s) in this database.
Experimentally validated
Total 20 [view]
Protein-Protein 20 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
Cellular Component
GO:0005739 mitochondrion
GO:0005840 ribosome
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Not yet available
Pathways
NETPATH
REACTOME
Organelle biogenesis and maintenance pathway
Mitochondrial translation pathway
Mitochondrial translation initiation pathway
Mitochondrial translation termination pathway
Mitochondrial translation elongation pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.715617 Hs.735072
RefSeq NM_022497
HUGO
OMIM
CCDS CCDS2622
HPRD 17594
IMGT
EMBL
GenPept
RNA Seq Atlas