Mus musculus Gene: Entpd3
Summary
InnateDB Gene IDBG-205190.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Entpd3
Gene Name ectonucleoside triphosphate diphosphohydrolase 3
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000041608
Encoded Proteins
ectonucleoside triphosphate diphosphohydrolase 3
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000168032:
ENTPD3 is similar to E-type nucleotidases (NTPases). NTPases, such as CD39, mediate catabolism of extracellular nucleotides. ENTPD3 contains 4 apyrase-conserved regions which is characteristic of NTPases. [provided by RefSeq, Jul 2008]
This gene encodes a plasma membrane-bound divalent cation-dependent E-type nucleotidase. The encoded protein is involved in the regulation of extracellular levels of ATP by hydrolysis of it and other nucleotides. Multiple transcript variants have been described. [provided by RefSeq, May 2014]
Gene Information
Type Protein coding
Genomic Location Chromosome 9:120539818-120568318
Strand Forward strand
Band F4
Transcripts
ENSMUST00000047687 ENSMUSP00000036830
ENSMUST00000143579
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0016787 hydrolase activity
GO:0017110 nucleoside-diphosphatase activity
GO:0017111 nucleoside-triphosphatase activity
Biological Process
GO:0009134 nucleoside diphosphate catabolic process
GO:0009143 nucleoside triphosphate catabolic process
Cellular Component
GO:0005886 plasma membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Not yet available
Pathways
NETPATH
REACTOME
KEGG
Pyrimidine metabolism pathway
Purine metabolism pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
Pyrimidine metabolism pathway
Purine metabolism pathway
INOH
Purine nucleotides nucleosides metabolism pathway
Pyrimidine nucleotides nucleosides metabolism pathway
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.76648
RefSeq NM_178676
OMIM
CCDS CCDS23629
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas