Version 5.4
Mus musculus Gene: Irs3
Summary
InnateDB Gene IDBG-205320.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Irs3
Gene Name insulin receptor substrate 3
Synonyms AA408304
Species Mus musculus
Ensembl Gene ENSMUSG00000047182
Encoded Proteins
IDBP-205322
insulin receptor substrate 3
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 5:137643032-137645714
Strand Reverse strand
Band G2
Transcripts
ENSMUST00000057314 ENSMUSP00000060844
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005158 insulin receptor binding
GO:0043548 phosphatidylinositol 3-kinase binding
Biological Process
Cellular Component
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0043231 intracellular membrane-bounded organelle
Orthologs
No orthologs found for this gene
Pathways
NETPATH
REACTOME
KEGG
mmu04930
Type II diabetes mellitus pathway
mmu04910
Insulin signaling pathway pathway
mmu04920
Adipocytokine signaling pathway pathway
INOH
INOH website
Insulin receptor signaling pathway
PID NCI
Cross-References
SwissProt
TrEMBL O54718
UniProt Splice Variant
Entrez Gene 16369
UniGene Mm.24486
RefSeq NM_010571
OMIM
CCDS CCDS19773
HPRD
IMGT
MGI ID MGI:1194882
MGI Symbol Irs3
EMBL AC124730 AF035948 AK030311 AK040947 CH466529
GenPept AAB88536 BAC26893 BAC30756 EDL19247
RNA Seq Atlas 16369

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca