Mus musculus Gene: Ano10
Summary
InnateDB Gene IDBG-205888.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Ano10
Gene Name anoctamin 10
Synonyms AI604832; Tmem16k
Species Mus musculus
Ensembl Gene ENSMUSG00000037949
Encoded Proteins
anoctamin 10
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a member of the anoctamin family, which in mammals is comprised of 10 members. Anoctamin proteins are proposed to have eight transmembrane domains with both termini facing the cytoplasm and a C-terminal domain of unknown function. While some members have been characterized as calcium-activated chloride channels, this protein is reported to inhibit anion conductance. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, Dec 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 9:122175879-122294374
Strand Reverse strand
Band F4
Transcripts
ENSMUST00000042546 ENSMUSP00000045214
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005227 calcium activated cation channel activity
GO:0005229 intracellular calcium activated chloride channel activity
Biological Process
GO:0006812 cation transport
GO:0006821 chloride transport
GO:1902476 chloride transmembrane transport
Cellular Component
GO:0005622 intracellular
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Not yet available
Pathways
NETPATH
REACTOME
Stimuli-sensing channels pathway
Orphan transporters pathway
Ion channel transport pathway
Transmembrane transport of small molecules pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
Stimuli-sensing channels pathway
Transmembrane transport of small molecules pathway
Orphan transporters pathway
Ion channel transport pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt Q8BH79
TrEMBL
UniProt Splice Variant
Entrez Gene 102566
UniGene Mm.474116 Mm.87676
RefSeq NM_133979 XM_006511913
OMIM
CCDS CCDS23645
HPRD
IMGT
MGI ID MGI:2143103
MGI Symbol Ano10
EMBL AK028391 AK046091 AK054163 AK079622 AK080947 BC002294 BC026421 BC099688
GenPept AAH02294 AAH26421 AAH99688 BAC25927 BAC32601 BAC35676 BAC37706 BAC38086
RNA Seq Atlas 102566