Version 5.4
Mus musculus Gene: Ap4m1
Summary
InnateDB Gene IDBG-205891.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Ap4m1
Gene Name adaptor-related protein complex AP-4, mu 1
Synonyms 4930443L05Rik; Ap4m4
Species Mus musculus
Ensembl Gene ENSMUSG00000019518
Encoded Proteins
IDBP-205893
adaptor-related protein complex AP-4, mu 1
IDBP-531749
adaptor-related protein complex AP-4, mu 1
IDBP-532228
adaptor-related protein complex AP-4, mu 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000221838:
This gene encodes a subunit of the heterotetrameric AP-4 complex. The encoded protein belongs to the adaptor complexes medium subunits family. This AP-4 complex is involved in the recognition and sorting of cargo proteins with tyrosine-based motifs from the trans-golgi network to the endosomal-lysosomal system. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 5:138172002-138178708
Strand Forward strand
Band G2
Transcripts
ENSMUST00000019662 ENSMUSP00000019662
ENSMUST00000151318 ENSMUSP00000121338
ENSMUST00000157031
ENSMUST00000143241 ENSMUSP00000123770
ENSMUST00000155745
ENSMUST00000142687
ENSMUST00000134100
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.
Predicted by orthology
Total 6 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0006810 transport
GO:0006886 intracellular protein transport
GO:0006895 Golgi to endosome transport
GO:0016192 vesicle-mediated transport
Cellular Component
GO:0005802 trans-Golgi network
GO:0005905 coated pit
GO:0016020 membrane
GO:0030131 clathrin adaptor complex
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000221838
View Gene Order
ENSBTAG00000002881
Not yet available
Pathways
NETPATH
REACTOME
KEGG
mmu04142
Lysosome pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
hsa04142
Lysosome pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.113205
RefSeq NM_021392
OMIM
CCDS CCDS19794
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca