Version 5.4
Mus musculus Gene: Pyhin1
Summary
InnateDB Gene IDBG-205927.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Pyhin1
Gene Name pyrin and HIN domain family, member 1
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000043263
Encoded Proteins
IDBP-205929
pyrin and HIN domain family, member 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
InnateDB Annotation
Summary
PMID 23045604
Pyhin1 is an activator of the STING-dependent IFN and ASC-dependent inflammasome in antiviral innate immunity.
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 1:173630859-173647928
Strand Forward strand
Band H3
Transcripts
ENSMUST00000056071 ENSMUSP00000061900
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0035458 cellular response to interferon-beta
GO:0045087 innate immune response (InnateDB)
Cellular Component
GO:0005634 nucleus
Orthologs
No orthologs found for this gene
Cross-References
SwissProt Q8BV49
TrEMBL
UniProt Splice Variant
Entrez Gene 236312
UniGene Mm.428673 Mm.447
RefSeq NM_175026
OMIM
CCDS CCDS35791
HPRD
IMGT
MGI ID MGI:2138243
MGI Symbol Pyhin1
EMBL AK040884 AK076726 AK080371 AK150817 BC096384 BC107378 BC107379
GenPept AAH96384 AAI07379 AAI07380 BAC30731 BAC36457 BAC37894 BAE29880
RNA Seq Atlas 236312

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca