Version 5.4
Mus musculus Gene: Uts2
Summary
InnateDB Gene IDBG-205948.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Uts2
Gene Name urotensin 2
Synonyms prepro-UII; Ucn2; UII
Species Mus musculus
Ensembl Gene ENSMUSG00000028963
Encoded Proteins
IDBP-205950
urotensin 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 4:150997097-151001810
Strand Forward strand
Band E2
Transcripts
ENSMUST00000030803 ENSMUSP00000030803
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0005179 hormone activity
Biological Process
GO:0001666 response to hypoxia
GO:0003105 negative regulation of glomerular filtration
GO:0007204 positive regulation of cytosolic calcium ion concentration
GO:0008217 regulation of blood pressure
GO:0010459 negative regulation of heart rate
GO:0010460 positive regulation of heart rate
GO:0010763 positive regulation of fibroblast migration
GO:0010841 positive regulation of circadian sleep/wake cycle, wakefulness
GO:0032224 positive regulation of synaptic transmission, cholinergic
GO:0032967 positive regulation of collagen biosynthetic process
GO:0033574 response to testosterone
GO:0035811 negative regulation of urine volume
GO:0035814 negative regulation of renal sodium excretion
GO:0042312 regulation of vasodilation
GO:0042493 response to drug
GO:0045597 positive regulation of cell differentiation
GO:0045766 positive regulation of angiogenesis
GO:0045776 negative regulation of blood pressure
GO:0045777 positive regulation of blood pressure
GO:0045909 positive regulation of vasodilation
GO:0046005 positive regulation of circadian sleep/wake cycle, REM sleep
GO:0046676 negative regulation of insulin secretion
GO:0048146 positive regulation of fibroblast proliferation
Cellular Component
GO:0005576 extracellular region
GO:0005615 extracellular space
Orthologs
No orthologs found for this gene
Pathways
NETPATH
REACTOME
REACT_223625
GPCR downstream signaling pathway
REACT_254215
Signaling by GPCR pathway
REACT_261161
Class A/1 (Rhodopsin-like receptors) pathway
REACT_188573
Gastrin-CREB signalling pathway via PKC and MAPK pathway
REACT_231468
GPCR ligand binding pathway
REACT_235286
Peptide ligand-binding receptors pathway
REACT_207651
G alpha (q) signalling events pathway
REACT_188257
Signal Transduction pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt Q9QZQ3
TrEMBL Q541G7
UniProt Splice Variant
Entrez Gene 24111
UniGene Mm.89984
RefSeq NM_011910
OMIM
CCDS CCDS18977
HPRD
IMGT
MGI ID MGI:1346329
MGI Symbol Uts2
EMBL AF172175 AY065984 BC107299 BC107300 CH466594
GenPept AAD55767 AAI07300 AAI07301 AAL55430 EDL14901
RNA Seq Atlas 24111

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca