Version 5.4
Mus musculus Gene: Ric3
Summary
InnateDB Gene IDBG-206083.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Ric3
Gene Name resistance to inhibitors of cholinesterase 3 homolog (C. elegans)
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000048330
Encoded Proteins
IDBP-206085
resistance to inhibitors of cholinesterase 3 homolog (C. elegans)
IDBP-400303
resistance to inhibitors of cholinesterase 3 homolog (C. elegans)
IDBP-541189
resistance to inhibitors of cholinesterase 3 homolog (C. elegans)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000166405:
The protein encoded by this gene promotes functional expression of homomeric nicotinic acetylcholine receptors at the cell surface. It enhances currents generated by these receptors by expediting receptor transport to the cell surface and by increasing receptor number. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 7:109034312-109083331
Strand Reverse strand
Band E3
Transcripts
ENSMUST00000055993 ENSMUSP00000056990
ENSMUST00000120876 ENSMUSP00000112788
ENSMUST00000147580 ENSMUSP00000116669
ENSMUST00000133876
ENSMUST00000137385
ENSMUST00000129629
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0033130 acetylcholine receptor binding
GO:0044183 protein binding involved in protein folding
Biological Process
GO:0006457 protein folding
GO:0007204 positive regulation of cytosolic calcium ion concentration
GO:0007271 synaptic transmission, cholinergic
GO:0043623 cellular protein complex assembly
Cellular Component
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0016021 integral component of membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000166405
View Gene Order
ENSBTAG00000004863
Not yet available
Cross-References
SwissProt Q8BPM6
TrEMBL D3YTZ9 F7CE80
UniProt Splice Variant
Entrez Gene 320360
UniGene Mm.404647 Mm.71007
RefSeq NM_001038624 XM_006507941 XM_006507942 XM_006507943
OMIM
CCDS CCDS21733
HPRD
IMGT
MGI ID MGI:2443887
MGI Symbol Ric3
EMBL AC121989 AC167362 AK053760 AK082275 AK149334 BC059258
GenPept AAH59258 BAC35510 BAC38452 BAE28817
RNA Seq Atlas 320360

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca