Version 5.4
Mus musculus Gene: Vps16
Summary
InnateDB Gene IDBG-206436.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Vps16
Gene Name vacuolar protein sorting 16 (yeast)
Synonyms 1810074M16Rik
Species Mus musculus
Ensembl Gene ENSMUSG00000027411
Encoded Proteins
IDBP-206438
vacuolar protein sorting 16 (yeast)
IDBP-540698
vacuolar protein sorting 16 (yeast)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000215305:
Vesicle mediated protein sorting plays an important role in segregation of intracellular molecules into distinct organelles. Genetic studies in yeast have identified more than 40 vacuolar protein sorting (VPS) genes involved in vesicle transport to vacuoles. This gene encodes the human homolog of yeast class C Vps16 protein. The mammalian class C Vps proteins are predominantly associated with late endosomes/lysosomes, and like their yeast counterparts, may mediate vesicle trafficking steps in the endosome/lysosome pathway. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 2:130424339-130444269
Strand Forward strand
Band F1
Transcripts
ENSMUST00000028900 ENSMUSP00000028900
ENSMUST00000125973
ENSMUST00000128994 ENSMUSP00000115899
ENSMUST00000130258
ENSMUST00000132388
ENSMUST00000131220
ENSMUST00000137084
ENSMUST00000125098
ENSMUST00000134677
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 15 experimentally validated interaction(s) in this database.
They are also associated with 13 interaction(s) predicted by orthology.
Experimentally validated
Total 15 [view]
Protein-Protein 15 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 13 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003779 actin binding
GO:0005515 protein binding
GO:0051015 actin filament binding
Biological Process
GO:0006886 intracellular protein transport
GO:0046718 viral entry into host cell
Cellular Component
GO:0005737 cytoplasm
GO:0005765 lysosomal membrane
GO:0005768 endosome
GO:0005769 early endosome
GO:0005770 late endosome
GO:0005884 actin filament
GO:0030424 axon
GO:0030897 HOPS complex
GO:0043025 neuronal cell body
GO:0055037 recycling endosome
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000215305
View Gene Order
ENSBTAG00000001320
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.468329
RefSeq NM_030559 XM_006500430
OMIM
CCDS CCDS38242
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca