Version 5.4
Mus musculus Gene: Sbf2
Summary
InnateDB Gene IDBG-206528.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Sbf2
Gene Name SET binding factor 2
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000038371
Encoded Proteins
IDBP-206530
SET binding factor 2
IDBP-619996
SET binding factor 2
IDBP-619997
SET binding factor 2
IDBP-619998
SET binding factor 2
IDBP-619999
SET binding factor 2
IDBP-620001
SET binding factor 2
IDBP-620003
SET binding factor 2
IDBP-620004
SET binding factor 2
IDBP-620005
SET binding factor 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000133812:
This gene encodes a pseudophosphatase and member of the myotubularin-related protein family. This gene maps within the CMT4B2 candidate region of chromosome 11p15 and mutations in this gene have been associated with Charcot-Marie-Tooth Disease, type 4B2. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 7:110308013-110614922
Strand Reverse strand
Band E3
Transcripts
ENSMUST00000033058 ENSMUSP00000033058
ENSMUST00000164759 ENSMUSP00000132072
ENSMUST00000166020 ENSMUSP00000126217
ENSMUST00000165992
ENSMUST00000164599 ENSMUSP00000131927
ENSMUST00000169740
ENSMUST00000164525 ENSMUSP00000128340
ENSMUST00000165449
ENSMUST00000171378
ENSMUST00000164559 ENSMUSP00000128265
ENSMUST00000167880
ENSMUST00000171218 ENSMUSP00000129805
ENSMUST00000166885 ENSMUSP00000130476
ENSMUST00000167652 ENSMUSP00000127105
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0016791 phosphatase activity
GO:0017112 Rab guanyl-nucleotide exchange factor activity
GO:0019208 phosphatase regulator activity
GO:0019902 phosphatase binding
GO:0035091 phosphatidylinositol binding
GO:0042803 protein homodimerization activity
Biological Process
GO:0016311 dephosphorylation
GO:0032313 regulation of Rab GTPase activity
GO:0032851 positive regulation of Rab GTPase activity
GO:0050790 regulation of catalytic activity
GO:0051262 protein tetramerization
Cellular Component
GO:0005774 vacuolar membrane
GO:0016020 membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000133812
View Gene Order
ENSBTAG00000043981
Not yet available
Cross-References
SwissProt
TrEMBL E9PXF8 Q8BJ67
UniProt Splice Variant
Entrez Gene 319934
UniGene Mm.102970
RefSeq NM_177324 XM_006507928 XM_006507929 XM_006507926
OMIM
CCDS CCDS52361
HPRD
IMGT
MGI ID MGI:1921831
MGI Symbol Sbf2
EMBL AC122921 AC124472 AC154911 AK029568
GenPept BAC26517
RNA Seq Atlas 319934

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca