Version 5.4
Mus musculus Gene: Zfp238
Summary
InnateDB Gene IDBG-206756.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Zfp238
Gene Name zinc finger protein 238
Synonyms RP58; Zfp238; Znf238
Species Mus musculus
Ensembl Gene ENSMUSG00000063659
Encoded Proteins
IDBP-206758
zinc finger protein 238
IDBP-206760
zinc finger protein 238
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000179456:
C2H2-type zinc finger proteins, such as ZNF238, act on the molecular level as transcriptional activators or repressors and are involved in chromatin assembly (Becker et al., 1997 [PubMed 9568537]).[supplied by OMIM, Jan 2011]
This gene encodes a C2H2-type zinc finger protein which acts a transcriptional repressor of genes involved in neuronal development. The encoded protein recognizes a specific sequence motif and recruits components of chromatin to target genes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2013]
Gene Information
Type Protein coding
Genomic Location Chromosome 1:177444661-177450760
Strand Forward strand
Band H4
Transcripts
ENSMUST00000077225 ENSMUSP00000076463
ENSMUST00000094276 ENSMUSP00000091831
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 5 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0043565 sequence-specific DNA binding
GO:0046872 metal ion binding
Biological Process
GO:0000122 negative regulation of transcription from RNA polymerase II promoter
GO:0001701 in utero embryonic development
GO:0006351 transcription, DNA-templated
GO:0007519 skeletal muscle tissue development
GO:0021549 cerebellum development
GO:0021766 hippocampus development
GO:0021987 cerebral cortex development
GO:0045892 negative regulation of transcription, DNA-templated
GO:0048666 neuron development
GO:0048872 homeostasis of number of cells
GO:0051302 regulation of cell division
Cellular Component
GO:0005634 nucleus
GO:0015630 microtubule cytoskeleton
GO:0045171 intercellular bridge
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000179456
View Gene Order
ENSBTAG00000000385
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.330700 Mm.386369 Mm.485687
RefSeq NM_001012330 NM_013915 XM_006496889 XM_006496890 XM_006496891 XM_006496892 XM_006496893 XM_006496894 XM_006496895 XM_006496896
OMIM
CCDS CCDS15553 CCDS35800
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca