Mus musculus Gene: Adam33
Summary
InnateDB Gene IDBG-206833.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Adam33
Gene Name a disintegrin and metallopeptidase domain 33
Synonyms Adaml
Species Mus musculus
Ensembl Gene ENSMUSG00000027318
Encoded Proteins
a disintegrin and metallopeptidase domain 33
a disintegrin and metallopeptidase domain 33
a disintegrin and metallopeptidase domain 33
a disintegrin and metallopeptidase domain 33
a disintegrin and metallopeptidase domain 33
a disintegrin and metallopeptidase domain 33
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000149451:
This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. This protein is a type I transmembrane protein implicated in asthma and bronchial hyperresponsiveness. Alternative splicing of this gene results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 2:131050591-131063814
Strand Reverse strand
Band F1
Transcripts
ENSMUST00000052104 ENSMUSP00000052486
ENSMUST00000110232 ENSMUSP00000105861
ENSMUST00000128828
ENSMUST00000132436
ENSMUST00000135149 ENSMUSP00000122608
ENSMUST00000134742
ENSMUST00000149625
ENSMUST00000127343
ENSMUST00000132071
ENSMUST00000147333 ENSMUSP00000117097
ENSMUST00000124481
ENSMUST00000183552 ENSMUSP00000139344
ENSMUST00000184921 ENSMUSP00000139366
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004222 metalloendopeptidase activity
GO:0005515 protein binding
GO:0008270 zinc ion binding
Biological Process
GO:0006508 proteolysis
GO:0042035 regulation of cytokine biosynthetic process
GO:0042127 regulation of cell proliferation
Cellular Component
GO:0016021 integral component of membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Not yet available
Cross-References
SwissProt Q923W9
TrEMBL
UniProt Splice Variant
Entrez Gene 110751
UniGene Mm.108550
RefSeq NM_033615 XM_006498579 NM_001163529
OMIM
CCDS CCDS16753 CCDS50716
HPRD
IMGT
MGI ID MGI:1341813
MGI Symbol Adam33
EMBL AB059632 AB059633 AF386072 AF472524 AL833771 CH466519
GenPept AAK67164 AAL79834 BAB84336 BAB84337 CAM18045 EDL28296
RNA Seq Atlas 110751