Version 5.4
Homo sapiens Gene: KIF1C
Summary
InnateDB Gene IDBG-20772.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol KIF1C
Gene Name kinesin family member 1C
Synonyms LTXS1; SATX2; SAX2; SPAX2; SPG58
Species Homo sapiens
Ensembl Gene ENSG00000129250
Encoded Proteins
IDBP-20776
kinesin family member 1C
IDBP-761515
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The protein encoded by this gene is a member of the kinesin-like protein family. The family members are microtubule-dependent molecular motors that transport organelles within cells and move chromosomes during cell division. Mutations in this gene are a cause of spastic ataxia 2, autosomal recessive. [provided by RefSeq, May 2014]
Gene Information
Type Protein coding
Genomic Location Chromosome 17:4997948-5028401
Strand Forward strand
Band p13.2
Transcripts
ENST00000320785 ENSP00000320821
ENST00000574165 ENSP00000458697
ENST00000572959
ENST00000573815
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 19 experimentally validated interaction(s) in this database.
Experimentally validated
Total 19 [view]
Protein-Protein 19 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003774 motor activity
GO:0003777 microtubule motor activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0008017 microtubule binding
GO:0044822 poly(A) RNA binding
Biological Process
GO:0006890 retrograde vesicle-mediated transport, Golgi to ER
GO:0007018 microtubule-based movement
GO:0008152 metabolic process
GO:0008219 cell death
Cellular Component
GO:0005783 endoplasmic reticulum
GO:0005794 Golgi apparatus
GO:0005871 kinesin complex
GO:0005874 microtubule
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000020821
View Gene Order
ENSBTAG00000001349
Not yet available
Cross-References
SwissProt
TrEMBL I3L1B1
UniProt Splice Variant
Entrez Gene 10749
UniGene Hs.435120
RefSeq NM_006612 XM_005256424
HUGO HGNC:6317
OMIM 603060
CCDS CCDS11065
HPRD 04342
IMGT
EMBL AC004771 AC012146
GenPept
RNA Seq Atlas 10749

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca