InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Gene: Polr3f

Summary

InnateDB Gene

IDBG-208527.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Polr3f

Gene Name

polymerase (RNA) III (DNA directed) polypeptide F

Synonyms

2810411G20Rik; 3010019O03Rik; 3110032A07Rik; RPC39; RPC6

Species

Mus musculus

Ensembl Gene

ENSMUSG00000027427

Encoded Proteins

IDBP-208529

polymerase (RNA) III (DNA directed) polypeptide F

IDBP-261163

polymerase (RNA) III (DNA directed) polypeptide F

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000132664:
The protein encoded by this gene is one of more than a dozen subunits forming eukaryotic RNA polymerase III (RNA Pol III), which transcribes 5S ribosomal RNA and tRNA genes. This protein has been shown to bind both TFIIIB90 and TBP, two subunits of RNA polymerase III transcription initiation factor IIIB (TFIIIB). Unlike most of the other RNA Pol III subunits, the encoded protein is unique to this polymerase. [provided by RefSeq, Jul 2008]
The protein encoded by this gene is one of more than a dozen subunits forming eukaryotic RNA polymerase III (RNA Pol III), which transcribes 5S ribosomal RNA and tRNA genes. This protein has been shown to bind both TFIIIB90 and TBP, two subunits of RNA polymerase III transcription initiation factor IIIB (TFIIIB). Unlike most of the other RNA Pol III subunits, the encoded protein is unique to this polymerase. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 2:144527718-144541995

Strand

Forward strand

Band

Transcripts

ENSMUST00000028914	ENSMUSP00000028914
ENSMUST00000110017	ENSMUSP00000105644
ENSMUST00000136999
ENSMUST00000155567
ENSMUST00000143292
ENSMUST00000152311
ENSMUST00000134051

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 26 interaction(s) predicted by orthology.

Experimentally validated
Total	3 [view]
Protein-Protein	3 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	26 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0001056	RNA polymerase III activity
GO:0003677	DNA binding
GO:0003899	DNA-directed RNA polymerase activity
GO:0005515	protein binding

Biological Process

GO:0006351	transcription, DNA-templated
GO:0006383	transcription from RNA polymerase III promoter
GO:0032728	positive regulation of interferon-beta production
GO:0045087	innate immune response
GO:0045089	positive regulation of innate immune response
GO:0051607	defense response to virus